Environmental and molecular regulation of diapause formation in a scyphozoan jellyfish.
Aurelia coerulea
diapause formation
jellyfish bloom
podocyst
single-cell RNA sequencing
Journal
Molecular ecology
ISSN: 1365-294X
Titre abrégé: Mol Ecol
Pays: England
ID NLM: 9214478
Informations de publication
Date de publication:
22 Dec 2023
22 Dec 2023
Historique:
revised:
05
12
2023
received:
13
09
2023
accepted:
11
12
2023
medline:
22
12
2023
pubmed:
22
12
2023
entrez:
22
12
2023
Statut:
aheadofprint
Résumé
Understanding the mechanisms underlying diapause formation is crucial for gaining insight into adaptive survival strategies across various species. In this study, we aimed to uncover the pivotal role of temperature and food availability in regulating diapausing podocyst formation in the jellyfish Aurelia coerulea. Furthermore, we explored the cellular and molecular basis of diapause formation using single-cell RNA sequencing. Our results showed cell-type-specific transcriptional landscapes during podocyst formation, which were underscored by the activation of specific transcription factors and signalling pathways. In addition, we found that the heat shock protein-coding genes HSC70 and HSP90a potentially act as hub genes that regulate podocyst formation. Finally, we mapped the single-cell atlas of diapausing podocysts and identified cell types involved in metabolism, environmental sensing, defence and development that may collectively contribute to the long-term survival and regulated excystment of diapausing podocysts. Taken together, the findings of this study provide novel insights into the molecular mechanisms that regulate diapause formation and contributes to a better understanding of adaptive survival strategies in a variety of ecological contexts.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e17249Subventions
Organisme : Taishan Scholars Program
ID : tsqn202211263
Organisme : National Natural Science Foundation of China
ID : 41876138
Organisme : National Science & Technology Fundamental Resources Investigation Program of China
ID : 2022FY100600
Organisme : Key Project of the NSFC-Shandong Joint Fund
ID : U2106208
Organisme : Strategic Priority Research Program of the Chinese Academy of Sciences
ID : XDA23050301
Organisme : Special Supporting Funding for Leading Talents above Provincial Level in Yantai.
Informations de copyright
© 2023 John Wiley & Sons Ltd.
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