Parallel Synthesis of Pyrazolone-Fused Cinnolines by the Palladium-Catalyzed [4 + 2] Annulation of Pyrazol-3-ones with Substituted Allenoates.

Journal

The Journal of organic chemistry
ISSN: 1520-6904
Titre abrégé: J Org Chem
Pays: United States
ID NLM: 2985193R

Informations de publication

Date de publication:
22 Dec 2023
Historique:
medline: 22 12 2023
pubmed: 22 12 2023
entrez: 22 12 2023
Statut: aheadofprint

Résumé

The synthesis of pyrazolone-fused cinnolines from pyrazol-3-ones and α,γ-substituted allenoates via a palladium-catalyzed C-H activation/annulation cascade was developed. Mechanistic studies revealed the course of the reaction. Initially,

Identifiants

DOI: 10.1021/acs.joc.3c02165 PMID: 38133555
pubmed: 38133555
doi: 10.1021/acs.joc.3c02165
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Wei-Jung Chiu (WJ)

Department of Applied Chemistry, National Yang-Ming Chiao-Tung University, 1001, Ta-Hseuh Road, Hsinchu 300-10, Taiwan.

Ting-Yen Chu (TY)

Department of Applied Chemistry, National Yang-Ming Chiao-Tung University, 1001, Ta-Hseuh Road, Hsinchu 300-10, Taiwan.

Indrajeet J Barve (IJ)

Department of Chemistry, MES Abasaheb Garware College, Pune 411004, Maharashtra, India.

Chung-Ming Sun (CM)

Department of Applied Chemistry, National Yang-Ming Chiao-Tung University, 1001, Ta-Hseuh Road, Hsinchu 300-10, Taiwan.
Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, 100, Shih-Chuan First Road, Kaohsiung 807-08, Taiwan.
ORCID: 0000-0002-1804-1578

Classifications MeSH