Initial experience of robotically assisted endometriosis surgery with a novel robotic system: first case series in a tertiary care center.

Docking Endometriosis Minimally invasive surgery Robotic surgery

Journal

Updates in surgery
ISSN: 2038-3312
Titre abrégé: Updates Surg
Pays: Italy
ID NLM: 101539818

Informations de publication

Date de publication:
22 Dec 2023
Historique:
received: 12 06 2023
accepted: 01 12 2023
medline: 22 12 2023
pubmed: 22 12 2023
entrez: 22 12 2023
Statut: aheadofprint

Résumé

Endometriosis is a benign disease requiring surgery if medical treatment can not achieve symptom control. Laparoscopy remains the gold standard and robotic assistance can be beneficial in complex cases. Robot-assisted radical endometriosis excision using the Hugo™ RAS system is a novel approach. The aim of this study is to describe its setting and outcomes in a series of patients in a robotic surgery center. Endometriosis patients who consecutively underwent robot-assisted surgery with the Hugo™ RAS system (Medtronic, USA) were retrospectively enrolled. Disease-specific symptoms before and after surgery, endometriosis stage, as well as perioperative and intraoperative variables including system setup were collected. Early post-operative complications (< 30 days) and follow-up (up to 3 months) were reported. All procedures were completed robotically. Port placement followed the "bridge" configuration with a "compact" docking. The median operative time was 186.5 min (IQR 174-220), the median estimated blood loss 50 ml (IQR 0-100). An intraoperative complication occurred in one patient (6.6%), a bladder laceration with postoperative antibiotic treatment. The median lenght of hospital stay (LOS) was 3 days (IQR 3-4). Surgery achieved a statistically significant decrease in symptoms: mean dysmenorrhea (9.50 ± 0.83 versus 1.7 ± 2.26; p = 0.001), dyschezia (4.27 ± 3.61 versus 2.40 ± 2.92; p = 0.026), dysuria (2.73 ± 3.39 versus 1.87 ± 2.41; p = 0.358), dyspareunia (6.53 ± 3.15 versus 2.93 ± 2.89; p = 0.002) and chronic pelvic pain (8.8 ± 1.20 versus 3.20 ± 2.39; p = 0.001). The integration of this platform in the described configuration was safe with regular perioperative outcomes and significant improvement in symptoms. Prospective comparative studies with a larger cohort and longer follow-up are needed to assess potential advantages over the current gold standard.

Identifiants

pubmed: 38133880
doi: 10.1007/s13304-023-01724-z
pii: 10.1007/s13304-023-01724-z
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Fondation de l'Avenir pour la Recherche Médicale Appliquée
ID : ANR-10-IAHU-02

Informations de copyright

© 2023. Italian Society of Surgery (SIC).

Références

Giudice LC (2010) Clinical practice. Endometriosis. N Engl J Med 362(25):2389–2398. https://doi.org/10.1056/nejmcp1000274
doi: 10.1056/nejmcp1000274 pubmed: 20573927 pmcid: 3108065
Ianieri MM, Buca DIP, Panaccio P, Cieri M, Francomano F, Liberati M (2017) Retroperitoneal endometriosis in postmenopausal woman causing deep vein thrombosis: case report and review of the literature. Clin Exp Obstet Gynecol 44(1):148–150
doi: 10.12891/ceog3306.2017 pubmed: 29714887
Dunselman GAJ, Vermeulen N, Becker C, Calhaz-Jorge C, D’Hooghe T, De Bie B et al (2014) ESHRE guideline: management of women with endometriosis. Hum Reprod Oxf Engl 29(3):400–412. https://doi.org/10.1093/humrep/det457
doi: 10.1093/humrep/det457
Luu TH, Uy-Kroh MJ (2017) New developments in surgery for endometriosis and pelvic pain. Clin Obstet Gynecol 60(2):245–251. https://doi.org/10.1097/GRF.0000000000000282
doi: 10.1097/GRF.0000000000000282 pubmed: 28288013
Restaino S, Mereu L, Finelli A, Spina MR, Marini G, Catena U et al (2020) Robotic surgery vs laparoscopic surgery in patients with diagnosis of endometriosis: a systematic review and meta-analysis. J Robot Surg 14(5):687–694. https://doi.org/10.1007/s11701-020-01061-y
doi: 10.1007/s11701-020-01061-y pubmed: 32146573
Peters BS, Armijo PR, Krause C, Choudhury SA, Oleynikov D (2018) Review of emerging surgical robotic technology. Surg Endosc 32(4):1636–1655. https://doi.org/10.1007/s00464-018-6079-2
doi: 10.1007/s00464-018-6079-2 pubmed: 29442240
Gueli Alletti S, Chiantera V, Arcuri G, Gioè A, Oliva R, Monterossi G et al (2022) Introducing the new surgical robot HUGO™ RAS: system description and docking settings for gynecological surgery. Front Oncol 12:898060. https://doi.org/10.3389/fonc.2022.898060
doi: 10.3389/fonc.2022.898060 pubmed: 35756633 pmcid: 9218341
Monterossi G, Pedone Anchora L, Gueli Alletti S, Fagotti A, Fanfani F, Scambia G (2022) The first European gynaecological procedure with the new surgical robot Hugo
Panico G, Campagna G, Caramazza D, Vacca L, Mastrovito S, Ercoli A et al (2023) HUGO(TM) RAS System in urogynaecology: the first nerve sparing sacral colpopexy for pelvic organ prolapse. Facts Views Vis ObGyn 15(1):83–7. https://doi.org/10.52054/FVVO.15.1.054
Revised American Society for Reproductive Medicine classification of endometriosis: 1996 (1997) Fertil Steril 67(5):817–21. https://doi.org/10.1016/s0015-0282(97)81391-x
Johnson NP, Hummelshoj L, Adamson GD, Keckstein J, Taylor HS, Abrao MS et al (2017) World Endometriosis Society consensus on the classification of endometriosis. Hum Reprod 32(2):315–324. https://doi.org/10.1093/humrep/dew293
doi: 10.1093/humrep/dew293 pubmed: 27920089
Delgado DA, Lambert BS, Boutris N, McCulloch PC, Robbins AB, Moreno MR et al (2018) Validation of digital visual analog scale pain scoring with a traditional paper-based visual analog scale in adults. J Am Acad Orthop Surg Glob Res Rev 2(3):e088. https://doi.org/10.5435/JAAOSGlobal-D-17-00088
doi: 10.5435/JAAOSGlobal-D-17-00088 pubmed: 30211382 pmcid: 6132313
Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240(2):205–213. https://doi.org/10.1097/01.sla.0000133083.54934.ae
doi: 10.1097/01.sla.0000133083.54934.ae pubmed: 15273542 pmcid: 1360123
Rosati A, Pavone M, Campolo F, De Cicco Nardone A, Raimondo D, Serracchioli R et al (2022) Surgical and functional impact of nerve-sparing radical hysterectomy for parametrial deep endometriosis: a single centre experience. Facts Views Vis ObGyn 14(2):121–7. https://doi.org/10.52054/FVVO.14.2.016
Ianieri MM, Raimondo D, Rosati A, Cocchi L, Trozzi R, Maletta M et al (2022) Impact of nerve-sparing posterolateral parametrial excision for deep infiltrating endometriosis on postoperative bowel, urinary, and sexual function. Int J Gynaecol Obstet Off Organ Int Fed Gynaecol Obstet 159(1):152–159. https://doi.org/10.1002/ijgo.14089
doi: 10.1002/ijgo.14089
Ianieri MM, Nardone ADC, Pavone M, Benvenga G, Pafundi MP, Campolo F et al (2023) Are ureterolysis for deep endometriosis really all the same? An anatomical classification proposal for ureterolysis: a single-center experience. Int J Gynaecol Obstet Off Organ Int Fed Gynaecol Obstet. https://doi.org/10.1002/ijgo.14790
Raffaelli M, Gallucci P, Voloudakis N, Pennestrì F, De Cicco R, Arcuri G et al (2023) The new robotic platform Hugo™ RAS for lateral transabdominal adrenalectomy: a first world report of a series of five cases. Updates Surg 75(1):217–225. https://doi.org/10.1007/s13304-022-01410-6
doi: 10.1007/s13304-022-01410-6 pubmed: 36333563
Nezhat CR, Stevens A, Balassiano E, Soliemannjad R (2015) Robotic-assisted laparoscopy vs conventional laparoscopy for the treatment of advanced stage endometriosis. J Minim Invas Gynecol 22(1):40–44. https://doi.org/10.1016/j.jmig.2014.06.002
doi: 10.1016/j.jmig.2014.06.002
Soto E, Luu TH, Liu X, Magrina JF, Wasson MN, Einarsson JI et al (2017) Laparoscopy vs. robotic surgery for endometriosis (LAROSE): a multicenter, randomized, controlled trial. Fertil Steril 107(4):996–1002.e3. https://doi.org/10.1016/j.fertnstert.2016.12.033
Nezhat FR, Sirota I (2014) Perioperative outcomes of robotic assisted laparoscopic surgery versus conventional laparoscopy surgery for advanced-stage endometriosis. JSLS 18(4):e201400094. https://doi.org/10.4293/JSLS.2014.00094
Magrina JF, Espada M, Kho RM, Cetta R, Chang YHH, Magtibay PM (2015) Surgical excision of advanced endometriosis: perioperative outcomes and impacting factors. J Minim Invas Gynecol 22(6):944–950. https://doi.org/10.1016/j.jmig.2015.04.016
doi: 10.1016/j.jmig.2015.04.016
Fanfani F, Restaino S, Ercoli A, Chiantera V, Fagotti A, Gallotta V et al (2016) Robotic versus laparoscopic surgery in gynecology: which should we use? Minerva Ginecol 68(4):423–430
pubmed: 26633042
Ercoli A, Bassi E, Ferrari S, Surico D, Fagotti A, Fanfani F et al (2017) Robotic-assisted conservative excision of retrocervical-rectal deep infiltrating endometriosis: a case series. J Minim Invas Gynecol 24(5):863–868. https://doi.org/10.1016/j.jmig.2017.03.011
doi: 10.1016/j.jmig.2017.03.011
Ianieri MM, Della Corte L, Campolo F, Cosentino F, Catena U, Bifulco G et al (2021) Indocyanine green in the surgical management of endometriosis: a systematic review. Acta Obstet Gynecol Scand 100(2):189–199. https://doi.org/10.1002/ijgo.14790
doi: 10.1002/ijgo.14790 pubmed: 32895911
Pavone M, Marescaux J, Seeliger B (2023) Current status of robotic abdominopelvic surgery. Show-Chwan Med J 22(3):467–473. https://doi.org/10.30185/scmj.202307/pp.0003
doi: 10.30185/scmj.202307/pp.0003

Auteurs

Matteo Pavone (M)

Dipartimento di Scienze per la Salute della Donna e del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli, IRCCS, UOC Ginecologia Oncologica, Largo Agostino Gemelli 8, 00168, Rome, Italy. matteopavone.21@gmail.com.
IHU Strasbourg , Institute of Image-Guided Surgery, Strasbourg, France. matteopavone.21@gmail.com.
IRCAD, Research Institute Against Digestive Cancer, Strasbourg, France. matteopavone.21@gmail.com.

Barbara Seeliger (B)

IHU Strasbourg , Institute of Image-Guided Surgery, Strasbourg, France.
IRCAD, Research Institute Against Digestive Cancer, Strasbourg, France.
Department of Visceral and Digestive Surgery, University Hospitals of Strasbourg, Strasbourg, France.
ICube, UMR 7357 CNRS, University of Strasbourg, Strasbourg, France.

Maria Vittoria Alesi (MV)

Dipartimento di Scienze per la Salute della Donna e del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli, IRCCS, UOC Ginecologia Oncologica, Largo Agostino Gemelli 8, 00168, Rome, Italy.

Marta Goglia (M)

IHU Strasbourg , Institute of Image-Guided Surgery, Strasbourg, France.
IRCAD, Research Institute Against Digestive Cancer, Strasbourg, France.
Department of Translational Medicine and Oncology, Sant'Andrea University Hospital, Sapienza University of Rome, Rome, Italy.

Jacques Marescaux (J)

IRCAD, Research Institute Against Digestive Cancer, Strasbourg, France.

Giovanni Scambia (G)

Dipartimento di Scienze per la Salute della Donna e del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli, IRCCS, UOC Ginecologia Oncologica, Largo Agostino Gemelli 8, 00168, Rome, Italy.

Manuel Maria Ianieri (MM)

Dipartimento di Scienze per la Salute della Donna e del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli, IRCCS, UOC Ginecologia Oncologica, Largo Agostino Gemelli 8, 00168, Rome, Italy.
Gynecology and Breast Care Center, Mater Olbia Hospital, Olbia, Italy.

Classifications MeSH