Taking the leap toward human-specific nonanimal methodologies: The need for harmonizing global policies for microphysiological systems.


Journal

Stem cell reports
ISSN: 2213-6711
Titre abrégé: Stem Cell Reports
Pays: United States
ID NLM: 101611300

Informations de publication

Date de publication:
05 Dec 2023
Historique:
received: 26 08 2023
revised: 20 11 2023
accepted: 20 11 2023
medline: 23 12 2023
pubmed: 23 12 2023
entrez: 22 12 2023
Statut: aheadofprint

Résumé

With a recent amendment, India joined other countries that have removed the legislative barrier toward the use of human-relevant methods in drug development. Here, global stakeholders weigh in on the urgent need to globally harmonize the guidelines toward the standardization of microphysiological systems. We discuss a possible framework for establishing scientific confidence and regulatory approval of these methods.

Identifiants

pubmed: 38134927
pii: S2213-6711(23)00457-5
doi: 10.1016/j.stemcr.2023.11.008
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests The authors declare no competing interests.

Auteurs

Surat Parvatam (S)

Humane Society International, Hyderabad, India. Electronic address: sparvatam@hsi.org.

David Pamies (D)

SCAHT - Swiss Centre for Applied Human Toxicology. University of Basel. Missionsstrasse 64, 4055 Basel, Switzerland.

Francesca Pistollato (F)

Humane Society International, Rue Belliard 40, 1040 Bruxelles, Belgium.

Sonja Beken (S)

Federal Agency for Medicines and Health Products, Brussels, Belgium.

Indumathi Mariappan (I)

Center for Ocular Regeneration, LV Prasad Eye Institute, Hyderabad, India.

Adrian Roth (A)

F. Hoffmann-La Roche, Basel, Switzerland.

Monica Piergiovanni (M)

European Commission, Joint Research Centre (JRC), Ispra, Italy.

Benoît G C Maisonneuve (B)

NETRI, Lyon, France.

Lorna Ewart (L)

Emulate Inc, 27 Drydock Avenue, Boston, MA, USA.

Abhijit Majumder (A)

Indian Institute of Technology Bombay (IITB), Mumbai, India.

Prajakta Dandekar (P)

Institute of Chemical Technology, Mumbai, India.

Rahul Date (R)

Jai Research Foundation, Gujarat, India.

Kasturi Mahadik (K)

Centre for Predictive Human Model Systems, Atal Incubation Centre-Centre for Cellular and Molecular Biology (AIC-CCMB), Hyderabad, India.

Saravanan Thiyagarajan (S)

Aurigene Oncology Limited, Bangalore, India.

Sandra Coecke (S)

European Commission, Joint Research Centre (JRC), Ispra, Italy.

Classifications MeSH