Cardioprotective Effect against Ischemia-Reperfusion Injury of PAK-200, a Dihydropyridine Analog with an Inhibitory Effect on Cl
PAK-200
cardioprotection
chloride current
dihydropyridine
ischemia and reperfusion
Journal
Biomolecules
ISSN: 2218-273X
Titre abrégé: Biomolecules
Pays: Switzerland
ID NLM: 101596414
Informations de publication
Date de publication:
29 Nov 2023
29 Nov 2023
Historique:
received:
27
10
2023
revised:
25
11
2023
accepted:
27
11
2023
medline:
23
12
2023
pubmed:
23
12
2023
entrez:
23
12
2023
Statut:
epublish
Résumé
We examined the effects of a dihydropyridine analog, PAK-200, on guinea pig myocardium during experimental ischemia and reperfusion. In isolated ventricular cardiomyocytes, PAK-200 (1 μM) had no effect on the basal peak inward and steady-state currents but inhibited the isoprenaline-induced time-independent Cl
Identifiants
pubmed: 38136589
pii: biom13121719
doi: 10.3390/biom13121719
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM