The Diagnostic Value of FibroTest and Hepascore as Non-Invasive Markers of Liver Fibrosis in Primary Sclerosing Cholangitis (PSC).

liver biopsy non-invasive markers of liver fibrosis and cirrhosis primary sclerosing cholangitis

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
07 Dec 2023
Historique:
received: 23 10 2023
revised: 29 11 2023
accepted: 04 12 2023
medline: 23 12 2023
pubmed: 23 12 2023
entrez: 23 12 2023
Statut: epublish

Résumé

The aim of this study was to evaluate the diagnostic usefulness of two non-invasive, validated, and patented markers of liver fibrosis, the Hepascore and FibroTest, in patients with primary sclerosing cholangitis (PSC). The study group consisted of 74 PSC patients and 38 healthy subjects. All patients had a liver biopsy. The Hepascore and FibroTest were calculated using specific algorithms. The ANOVA rank Kruskal-Wallis test revealed differences in the Hepascore and FibroTest between patients divided according to histological stage (

Identifiants

pubmed: 38137620
pii: jcm12247552
doi: 10.3390/jcm12247552
pii:
doi:

Types de publication

Journal Article

Langues

eng

Auteurs

Bogdan Cylwik (B)

Department of Pediatric Laboratory Diagnostics, Medical University of Bialystok, 15-274 Bialystok, Poland.

Alicja Bauer (A)

Department of Biochemistry and Molecular Biology, Centre of Postgraduate Medical Education, 01-813 Warsaw, Poland.

Ewa Gruszewska (E)

Department of Biochemical Diagnostics, Medical University of Bialystok, 15-269 Bialystok, Poland.

Kacper Gan (K)

Department of Internal Diseases and Gastroenterology, Provincial Welded Hospital, 15-278 Bialystok, Poland.

Marcin Kazberuk (M)

Department of Internal Diseases and Gastroenterology, Provincial Welded Hospital, 15-278 Bialystok, Poland.

Lech Chrostek (L)

Department of Biochemical Diagnostics, Medical University of Bialystok, 15-269 Bialystok, Poland.

Classifications MeSH