Frailty in Traumatic Brain Injury-The Significance of Temporal Muscle Thickness.

frailty outcome risk factors sarcopenia temporal muscle thickness (TMT) traumatic brain injury (TBI)

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
11 Dec 2023
Historique:
received: 27 10 2023
revised: 23 11 2023
accepted: 08 12 2023
medline: 23 12 2023
pubmed: 23 12 2023
entrez: 23 12 2023
Statut: epublish

Résumé

Temporal muscle thickness (TMT) on cranial CT scans has recently been identified as a prognostic imaging parameter for assessing a patient's baseline frailty. Here, we analyzed whether TMT correlates with Traumatic brain injury (TBI) severity and whether it can be used to predict outcome(s) after TBI. We analyzed the radiological and clinical data sets of 193 patients with TBI who were admitted to our institution and correlated the radiological data with clinical outcomes after stratification for TMT. Our analyses showed a significant association between high TMT and increased risk for intracranial hemorrhage ( High TMT was robustly associated with head trauma sequelae but was also associated with good clinical outcomes in TBI patients. These findings consolidate the significance of TMT as an objective marker of frailty in TBI patients; such measurements may ultimately be leveraged as prognostic indicators.

Sections du résumé

BACKGROUND BACKGROUND
Temporal muscle thickness (TMT) on cranial CT scans has recently been identified as a prognostic imaging parameter for assessing a patient's baseline frailty. Here, we analyzed whether TMT correlates with Traumatic brain injury (TBI) severity and whether it can be used to predict outcome(s) after TBI.
METHODS METHODS
We analyzed the radiological and clinical data sets of 193 patients with TBI who were admitted to our institution and correlated the radiological data with clinical outcomes after stratification for TMT.
RESULTS RESULTS
Our analyses showed a significant association between high TMT and increased risk for intracranial hemorrhage (
CONCLUSION CONCLUSIONS
High TMT was robustly associated with head trauma sequelae but was also associated with good clinical outcomes in TBI patients. These findings consolidate the significance of TMT as an objective marker of frailty in TBI patients; such measurements may ultimately be leveraged as prognostic indicators.

Identifiants

pubmed: 38137693
pii: jcm12247625
doi: 10.3390/jcm12247625
pii:
doi:

Types de publication

Journal Article

Langues

eng

Auteurs

Daniel Dubinski (D)

Department of Neurosurgery, University Medicine Rostock, 18057 Rostock, Germany.

Sae-Yeon Won (SY)

Department of Neurosurgery, University Medicine Rostock, 18057 Rostock, Germany.

Jonas Meyer-Wilmes (J)

Department of Neurosurgery, University Medicine Rostock, 18057 Rostock, Germany.

Svorad Trnovec (S)

Department of Neurosurgery, University Medicine Rostock, 18057 Rostock, Germany.

Artem Rafaelian (A)

Department of Neurosurgery, University Medicine Rostock, 18057 Rostock, Germany.

Bedjan Behmanesh (B)

Department of Neurosurgery, University Medicine Rostock, 18057 Rostock, Germany.

Daniel Cantré (D)

Institute of Diagnostic and Interventional Radiology, Pediatric Radiology and Neuroradiology, University Medicine Rostock, 18057 Rostock, Germany.

Peter Baumgarten (P)

Department of Neurosurgery, University Hospital, Schiller University Jena, 07747 Jena, Germany.

Nazife Dinc (N)

Department of Neurosurgery, University Hospital, Schiller University Jena, 07747 Jena, Germany.

Juergen Konczalla (J)

Department of Neurosurgery, Goethe-University Hospital, 60596 Frankfurt am Main, Germany.

Matthias Wittstock (M)

Department of Neurology, University Medicine Rostock, 18057 Rostock, Germany.

Joshua D Bernstock (JD)

Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

Thomas M Freiman (TM)

Department of Neurosurgery, University Medicine Rostock, 18057 Rostock, Germany.

Florian Gessler (F)

Department of Neurosurgery, University Medicine Rostock, 18057 Rostock, Germany.

Classifications MeSH