Synthesis of Quercetin-Loaded Silver Nanoparticles and Assessing Their Anti-Bacterial Potential.

antibacterial quercetin silver nanoparticles

Journal

Micromachines
ISSN: 2072-666X
Titre abrégé: Micromachines (Basel)
Pays: Switzerland
ID NLM: 101640903

Informations de publication

Date de publication:
25 Nov 2023
Historique:
received: 18 09 2023
revised: 26 10 2023
accepted: 23 11 2023
medline: 23 12 2023
pubmed: 23 12 2023
entrez: 23 12 2023
Statut: epublish

Résumé

The study delves into the multifaceted potential of quercetin (Qu), a phytoconstituent found in various fruits, vegetables, and medicinal plants, in combination with silver nanoparticles (AgNPs). The research explores the synthesis and characterization of AgNPs loaded with Qu and investigates their pharmaceutical applications, particularly focusing on antibacterial properties. The study meticulously evaluates Qu's identity, and physicochemical properties, reaffirming its suitability for pharmaceutical use. The development of Qu-loaded AgNPs demonstrates their high drug entrapment efficiency, ideal particle characteristics, and controlled drug release kinetics, suggesting enhanced therapeutic efficacy and reduced side effects. Furthermore, the research examines the antibacterial activity of Qu in different solvents, revealing distinct outcomes. Qu, both in methanol and water formulations, exhibits antibacterial activity against

Identifiants

pubmed: 38138323
pii: mi14122154
doi: 10.3390/mi14122154
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : This research was funded by Researchers Supporting Project number (RSPD2023R1087), King Saud University, Riyadh, Saudi Arabia
ID : RSPD2023R1087

Auteurs

Ritu Sharma (R)

School of Medical and Allied Sciences, K.R. Mangalam University, Gurugram 122103, India.

Parakh Basist (P)

School of Medical and Allied Sciences, K.R. Mangalam University, Gurugram 122103, India.
Department of Pharmacology, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110062, India.

Abdulsalam Alhalmi (A)

Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110062, India.

Rahmuddin Khan (R)

Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110062, India.

Omar M Noman (OM)

Department of Pharmacognosy, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.

Ahmad Alahdab (A)

Institute of Pharmacy, Clinical Pharmacy, University of Greifswald, Friedrich-Ludwig-Jahn-Str. 17, 17489 Greifswald, Germany.

Classifications MeSH