A Robust and Efficient FRET-Based Assay for Cannabinoid Receptor Ligands Discovery.
CB1R
CB2R
HTRF
HTS
binding
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
15 Dec 2023
15 Dec 2023
Historique:
received:
31
10
2023
revised:
07
12
2023
accepted:
08
12
2023
medline:
23
12
2023
pubmed:
23
12
2023
entrez:
23
12
2023
Statut:
epublish
Résumé
The identification of new modulators for Cannabinoid Receptors (CBRs) has garnered significant attention in drug discovery over recent years, owing to their manifold pathophysiological implications. In the context of hit identification, the availability of robust and sensitive high-throughput screening assays is essential to enhance the likelihood of success. In this study, we present the development and validation of a Tag-lite
Identifiants
pubmed: 38138600
pii: molecules28248107
doi: 10.3390/molecules28248107
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Xunta de Galicia
ID : PID2020-113430RB-I00
Organisme : the Consellería de Cultura, Educación e Ordenación Universitaria of the Galician Government
ID : D431B 2020/43
Organisme : the European Regional Development Fund (ERDF).
ID : N/A