Inapparent Tick-Borne Orthoflavivirus Infection in
Powassan virus
TBE vaccine
antibody spectrum
cognitive impairment
cross-reactive antibodies
flaviviruses
inapparent infection
orthoflaviviruses
tick-borne encephalitis virus
Journal
Vaccines
ISSN: 2076-393X
Titre abrégé: Vaccines (Basel)
Pays: Switzerland
ID NLM: 101629355
Informations de publication
Date de publication:
25 Nov 2023
25 Nov 2023
Historique:
received:
03
10
2023
revised:
17
11
2023
accepted:
23
11
2023
medline:
23
12
2023
pubmed:
23
12
2023
entrez:
23
12
2023
Statut:
epublish
Résumé
Tick-borne encephalitis virus (TBEV) and Powassan virus (POWV) are neurotropic tick-borne orthoflaviviruses. They cause mostly asymptomatic infections in hosts, but severe forms with CNS involvement can occur. Studying the early stages of viral infections in humans is challenging, and appropriate animal models are essential for understanding the factors determining the disease severity and for developing emergency prophylaxis and treatment options. In this work, we assessed the model of the early stages of TBEV and POWV mono- and co-infections in
Identifiants
pubmed: 38140159
pii: vaccines11121754
doi: 10.3390/vaccines11121754
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Ministry of Science and Higher Education of Russia
ID : 0837-2019-0003, 0837-2019-0007
Organisme : Chumakov Institute of Poliomyelitis and Viral Encephalitides
ID : 3