Cholesterol Metabolism in Antigen-Presenting Cells and HIV-1 Trans-Infection of CD4

HIV-1 antigen-presenting cells antiretroviral therapy cholesterol metabolism immunometabolism latent reservoir non-progressor trans-infection

Journal

Viruses
ISSN: 1999-4915
Titre abrégé: Viruses
Pays: Switzerland
ID NLM: 101509722

Informations de publication

Date de publication:
29 Nov 2023
Historique:
received: 25 10 2023
revised: 28 11 2023
accepted: 28 11 2023
medline: 23 12 2023
pubmed: 23 12 2023
entrez: 23 12 2023
Statut: epublish

Résumé

Antiretroviral therapy (ART) provides an effective method for managing HIV-1 infection and preventing the onset of AIDS; however, it is ineffective against the reservoir of latent HIV-1 that persists predominantly in resting CD4

Identifiants

pubmed: 38140588
pii: v15122347
doi: 10.3390/v15122347
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NIH HHS
ID : R01 - AI162615
Pays : United States

Auteurs

Daniel Okpaise (D)

Department of Medicine, Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

Nicolas Sluis-Cremer (N)

Department of Medicine, Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

Giovanna Rappocciolo (G)

Department of Medicine, Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

Charles R Rinaldo (CR)

Department of Medicine, Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

Classifications MeSH