The use of CytoSorb in acute oral mercuric chloride poisoning at a potentially lethal dose.

CVVHDF Ci-Ca CytoSorb elimination of inorganic mercury compound mercuric chloride poisoning renal replacement therapy

Journal

The International journal of artificial organs
ISSN: 1724-6040
Titre abrégé: Int J Artif Organs
Pays: United States
ID NLM: 7802649

Informations de publication

Date de publication:
23 Dec 2023
Historique:
medline: 24 12 2023
pubmed: 24 12 2023
entrez: 24 12 2023
Statut: aheadofprint

Résumé

The study aims to present a case of acute mercuric chloride poisoning treated successfully with continuous renal replacement therapy using the CytoSorb filter. A 21-year-old female patient after a suicide attempt by intentional ingestion of mercuric chloride, was admitted to the hospital with features of multiple organ damage for specific treatment. The performed laboratory tests confirmed high levels of mercury in the blood (1051 μg/L) and urine (22,960 μg/L). Due to acute renal failure, continuous renal replacement therapy (CRRT) CVVHD Ci-Ca was initiated; the procedure was then converted to CVVHDF Ci-Ca with ultrafiltration to optimise therapy, and CytoSorb was added to the artificial kidney system on day 3. Specific antidote therapy (DMPS) was administered concurrently. The ongoing treatment resulted in a reduction in subjective complaints, a decrease in blood mercury levels to 580 μg/L, and an improvement in parenchymal organ function. In the event of poisoning with inorganic mercury compounds (mercuric chloride), continuous renal replacement therapy using the CytoSorb filter as an extracorporeal blood purification method may be considered.

Identifiants

pubmed: 38142295
doi: 10.1177/03913988231215631
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3913988231215631

Déclaration de conflit d'intérêts

Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Auteurs

Anna Krakowiak (A)

Clinic of Anaesthesiology and Intensive Care, Central Clinical Hospital of the Medical University of Łódź, Lodz, Poland.
Centre for Physicians Training in Public Health, Nofer Institute of Occupational Medicine in Łódź, Lodz, Poland.

Beata Janasik (B)

Department of Biological and Enviromental Monitoring, Nofer Institute of Occupational Medicine in Łódź, Lodz, Poland.

Łukasz Sadowski (Ł)

Clinic of Anaesthesiology and Intensive Care, Central Clinical Hospital of the Medical University of Łódź, Lodz, Poland.

Katarzyna Szwabe (K)

Department of Laboratory Diagnostics and Clinical Biochemistry, Medical University of Łódź, Lodz, Poland.
Medical Diagnostic Laboratory, Central Clinical Hospital of Medical University of Łódź, Lodz, Poland.

Tomasz Wiśniewski (T)

Clinic of Anaesthesiology and Intensive Care, Central Clinical Hospital of the Medical University of Łódź, Lodz, Poland.

Małgorzata Anna Rak (M)

Department of Emergency Medicine, Faculty of Medical Sciences, Academy of Silesia, Katowice, Poland.

Waldemar Machała (W)

Clinic of Anaesthesiology and Intensive Care, Central Clinical Hospital of the Medical University of Łódź, Lodz, Poland.

Classifications MeSH