Fluorometric determination of ornidazole by using BSA coated copper nanoclusters as a novel turn off sensor.
Copper nanocluster
fluorescence sensor
ornidazole
pharmaceuticals
Journal
Turkish journal of chemistry
ISSN: 1300-0527
Titre abrégé: Turk J Chem
Pays: Turkey
ID NLM: 101259104
Informations de publication
Date de publication:
2022
2022
Historique:
received:
15
09
2021
revised:
27
04
2022
accepted:
06
12
2021
medline:
6
12
2021
pubmed:
6
12
2021
entrez:
25
12
2023
Statut:
epublish
Résumé
A fluorescent probe based on bovine serum albumin stabilized copper nanoclusters (BSA-CuNCs) was developed for the selective and sensitive determination of ornidazole (ORN). The nanoclusters were synthesized via a one-pot hydrothermal process in basic media. The synthesized and characterized BSA-CuNCs have less than 3 nm particle size and exhibited blue emission at 405 nm when excited at 325 nm. Synthesized and characterized nanoclusters were successfully applied as a turn-off fluorescent probe for the determination of ORN in pharmaceutical dosage forms. The quenching mechanism created an was inner filter effect (IFE). The method was linear in the concentration range of 0.52-13.56
Identifiants
pubmed: 38143469
doi: 10.3906/kim-2109-41
pii: turkjchem-46-2-475
pmc: PMC10734750
doi:
Types de publication
Journal Article
Langues
eng
Pagination
475-486Informations de copyright
© TÜBİTAK.