Minimal Invasive Versus Open Surgery for Colorectal Liver Metastases: A Multicenter German StuDoQ|Liver Registry-Based Cohort Analysis in Germany.

colorectal liver metastasis liver resection minimal invasive liver surgery

Journal

Annals of surgery open : perspectives of surgical history, education, and clinical approaches
ISSN: 2691-3593
Titre abrégé: Ann Surg Open
Pays: United States
ID NLM: 101769928

Informations de publication

Date de publication:
Dec 2023
Historique:
received: 01 03 2023
accepted: 25 09 2023
medline: 25 12 2023
pubmed: 25 12 2023
entrez: 25 12 2023
Statut: epublish

Résumé

To compare the outcome of minimally invasive liver surgery (MILS) to open liver surgery (OLS) for resection of colorectal liver metastases (CRLM) on a nationwide level. Colorectal cancer is the third most common malignancy worldwide. Up to 50% of all patients with colorectal cancer develop CRLM. MILS represents an attractive alternative to OLS for treatment of CRLM. Retrospective cohort study using the prospectively recorded German Quality management registry for liver surgery. Propensity-score matching was performed to account for variance in the extent of resection and patient demographics. In total, 1037 patients underwent liver resection for CRLM from 2019 to 2021. MILS was performed in 31%. Operative time was significantly longer in MILS (234 MILS is not the standard for resection of CRLM in Germany. Drawbacks, such as a longer operative time remain. However, if technically possible, MILS is a reasonable alternative to OLS for resection of CRLM, with comparable postoperative complications, reduced LOS, and equal oncological radicality.

Sections du résumé

Objective UNASSIGNED
To compare the outcome of minimally invasive liver surgery (MILS) to open liver surgery (OLS) for resection of colorectal liver metastases (CRLM) on a nationwide level.
Background UNASSIGNED
Colorectal cancer is the third most common malignancy worldwide. Up to 50% of all patients with colorectal cancer develop CRLM. MILS represents an attractive alternative to OLS for treatment of CRLM.
Methods UNASSIGNED
Retrospective cohort study using the prospectively recorded German Quality management registry for liver surgery. Propensity-score matching was performed to account for variance in the extent of resection and patient demographics.
Results UNASSIGNED
In total, 1037 patients underwent liver resection for CRLM from 2019 to 2021. MILS was performed in 31%. Operative time was significantly longer in MILS (234
Conclusion UNASSIGNED
MILS is not the standard for resection of CRLM in Germany. Drawbacks, such as a longer operative time remain. However, if technically possible, MILS is a reasonable alternative to OLS for resection of CRLM, with comparable postoperative complications, reduced LOS, and equal oncological radicality.

Identifiants

pubmed: 38144486
doi: 10.1097/AS9.0000000000000350
pmc: PMC10735166
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e350

Informations de copyright

Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc.

Déclaration de conflit d'intérêts

The authors declare that they have nothing to disclose.

Auteurs

Simon Moosburner (S)

From the Department of Surgery, Experimental Surgery, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Clinician Scientist Program, Berlin Institute of Health at Charité-Universitätsmedizin Berlin, BIH Academy, Berlin, Germany.

Chiara Kettler (C)

From the Department of Surgery, Experimental Surgery, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

Karl H Hillebrandt (KH)

From the Department of Surgery, Experimental Surgery, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Clinician Scientist Program, Berlin Institute of Health at Charité-Universitätsmedizin Berlin, BIH Academy, Berlin, Germany.

Moritz Blank (M)

From the Department of Surgery, Experimental Surgery, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

Hannes Freitag (H)

From the Department of Surgery, Experimental Surgery, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

Sebastian Knitter (S)

From the Department of Surgery, Experimental Surgery, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

Felix Krenzien (F)

From the Department of Surgery, Experimental Surgery, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Clinician Scientist Program, Berlin Institute of Health at Charité-Universitätsmedizin Berlin, BIH Academy, Berlin, Germany.

Nora Nevermann (N)

From the Department of Surgery, Experimental Surgery, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

Igor M Sauer (IM)

From the Department of Surgery, Experimental Surgery, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

Dominik P Modest (DP)

Department of Hematology, Oncology, and Cancer Immunology | CVKCharité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin.

Georg Lurje (G)

From the Department of Surgery, Experimental Surgery, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

Robert Öllinger (R)

From the Department of Surgery, Experimental Surgery, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

Wenzel Schöning (W)

From the Department of Surgery, Experimental Surgery, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

Jens Werner (J)

Department of General, Visceral, Transplantation, Vascular and Thoracic Surgery, Hospital of the LMU Munich, Campus Großhadern, Munich.

Maximilian Schmeding (M)

Department of Surgery, Clinic Dortmund gGmbH, Dortmund.

Johann Pratschke (J)

From the Department of Surgery, Experimental Surgery, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

Nathanael Raschzok (N)

From the Department of Surgery, Experimental Surgery, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Clinician Scientist Program, Berlin Institute of Health at Charité-Universitätsmedizin Berlin, BIH Academy, Berlin, Germany.

Classifications MeSH