The enrofloxacin pollution control from fish to environment.

Enrofloxacin (ENR) is used to prevent and treat fish diseases widely. However, its pollution is increasing public concern on human health and aquatic ecosystem safety. This review aims to find its pollution mechanisms and control way. It is found: (1) The excessive ENR administration is the main source, the sediment ENR escaping from photolysis is the secondary ENR pollution source; (2) The ENR-rich fishes were benthic lipid-rich fishes which can simultaneously absorb administration ENR and sediment ENR, the ENR bioaccumulation is positively related to the fish habitats ENR level and fish lipids content; (3) The ENR t1/2 varies with fish age, body weight, feedstuff lipids and crude fiber level, temperature, salinity, administration mode and dose; Consequently, the first control way is to conduct the minimum inhibitory concentration ENR, combining herbal medicines with antibacterial and detoxification functions. The second way is to develop the enrichment and removal techniques for sediment ENR.

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Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.