Locus coeruleus tyrosine hydroxylase positive neurons mediated the peripheral and central therapeutic effects of transcutaneous auricular vagal nerve stimulation (taVNS) in MRL/lpr mice.
Locus coeruleus
Systemic lupus erythematosus
Transcutaneous auricular vagus nerve stimulation
Vagus nerve stimulation
Journal
Brain stimulation
ISSN: 1876-4754
Titre abrégé: Brain Stimul
Pays: United States
ID NLM: 101465726
Informations de publication
Date de publication:
23 Dec 2023
23 Dec 2023
Historique:
received:
03
10
2023
revised:
16
12
2023
accepted:
19
12
2023
medline:
26
12
2023
pubmed:
26
12
2023
entrez:
25
12
2023
Statut:
aheadofprint
Résumé
This study aims to investigate the effects of transcutaneous auricular vagus nerve stimulation (taVNS) on the development of systemic lupus erythematosus (SLE) in MRL/lpr mice. MRL/lpr mice were treated with taVNS for ten weeks. Locus coeruleus (LC) tyrosine hydroxylase positive (TH TaVNS activated the TH This study provides direct evidence that taVNS can retard the development of peripheral and central symptoms of SLE, which is mediated by the LC TH
Identifiants
pubmed: 38145753
pii: S1935-861X(23)01973-3
doi: 10.1016/j.brs.2023.12.008
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2023. Published by Elsevier Inc.
Déclaration de conflit d'intérêts
Declaration of competing interest We declare that we have no financial and personal relationships with other people or organizations that can inappropriately influence our work, there is no professional or other personal interest of any nature or kind in any product, service and/or company that could be construed as influencing the position presented in, or the review of, the manuscript entitled, “Locus coeruleus tyrosine hydroxylase positive neurons mediated the peripheral and central therapeutic effects of transcutaneous auricular vagal nerve stimulation (taVNS) in MRL/lpr mice”.