Does cryotherapy decrease the local recurrence rate in the treatment of an Aneurysmal Bone Cyst? A comparative assessment.

Aneurysmal Bone Cyst Local adjuvant MSTS93 cryoablation local recurrence surgical complication

Journal

Journal of orthopaedic research : official publication of the Orthopaedic Research Society
ISSN: 1554-527X
Titre abrégé: J Orthop Res
Pays: United States
ID NLM: 8404726

Informations de publication

Date de publication:
25 Dec 2023
Historique:
medline: 26 12 2023
pubmed: 26 12 2023
entrez: 25 12 2023
Statut: aheadofprint

Résumé

Curettage with or without the use of adjuvants is standard of care in treatment of an Aneurysmal Bone Cyst (ABC). Historically, our approach combined curettage, high speed burr drilling and cryo-ablation. However, treatments varied based on age, tumor location and surgeon preference. We asked:(1) Does cryoablation in addition to curettage and burr drilling decrease the local recurrence rates? (2) Are there any risk factors for local recurrence rate? (3) Does cryoablation improve postsurgical functional outcomes in these patients? Patients treated for an ABC, between January 2006 and December 2019 were included in this retrospective analysis. Patient and surgical characteristics, such as age, gender, tumor location, type of treatment, time of follow-up, recurrence rate and functional outcome measured by the MSTS93 score were compared between those treated with and without cryo-ablation. Both groups, without cryo-ablation (n-88) and with cryo-ablation (n-42), showed no significant difference in local recurrence rates (9.1% vs 7.1%, p-0.553) and functional outcomes as measured by the MSTS 93 score (28.9 vs. 27.8, p-0262). Risk factors analyzed did not significantly affect local recurrence risk, except for secondary ABC diagnosis (p=0.017). The cryo-ablation group had a more extended follow-up (45.6 vs 73.2 months, p<0.001), reflecting shift in practice over time. We found no significant difference in local recurrence rate or functional outcome in patients treated with or without cryo-ablation. Formal curettage with additional high-speed burr drilling provides effective tumor control and favorable functional outcomes, negating the need for adjuvant cryo-ablation. This article is protected by copyright. All rights reserved.

Identifiants

pubmed: 38146068
doi: 10.1002/jor.25775
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

This article is protected by copyright. All rights reserved.

Auteurs

Eran Levanon (E)

Goldman School of Medicine, Ben Gurion university, Beer Sheva, Israel.

Omri Merose (O)

National Unit of Orthopedic Oncology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Ortal Segal (O)

National Unit of Orthopedic Oncology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Solomon Dadia (S)

National Unit of Orthopedic Oncology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Amir Sternheim (A)

National Unit of Orthopedic Oncology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Dror Levin (D)

Department of Pediatric Hemato-Oncology, Dana Children's Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Osnat Sher (O)

Institute of Pathology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Yair Gortzak (Y)

National Unit of Orthopedic Oncology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
The Pediatric Orthopedic Oncology Unit, Dana Children's Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Classifications MeSH