The role of α-synuclein in exocytosis.
Exocytosis
Fusion pore
Neurotransmitter release
Parkinson's disease
Synaptic vesicle
Synuclein
Journal
Experimental neurology
ISSN: 1090-2430
Titre abrégé: Exp Neurol
Pays: United States
ID NLM: 0370712
Informations de publication
Date de publication:
24 Dec 2023
24 Dec 2023
Historique:
received:
24
08
2023
revised:
28
11
2023
accepted:
19
12
2023
medline:
27
12
2023
pubmed:
27
12
2023
entrez:
26
12
2023
Statut:
aheadofprint
Résumé
The pathogenesis of degeneration in Parkinson's disease (PD) remains poorly understood but multiple lines of evidence have converged on the presynaptic protein α-synuclein (αsyn). αSyn has been shown to regulate several cellular processes, however, its normal function remains poorly understood. In this review, we will specifically focus on its role in exocytosis.
Identifiants
pubmed: 38147972
pii: S0014-4886(23)00353-9
doi: 10.1016/j.expneurol.2023.114668
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
114668Informations de copyright
Copyright © 2023. Published by Elsevier Inc.