Donor Proteinuria and Allograft Function in Kidney Transplantation: Short- and Long-Term Results From a Retrospective Cohort Study.

allocation graft survival kidney transplantation patient survival proteinuria

Journal

Transplant international : official journal of the European Society for Organ Transplantation
ISSN: 1432-2277
Titre abrégé: Transpl Int
Pays: Switzerland
ID NLM: 8908516

Informations de publication

Date de publication:
2023
Historique:
received: 22 08 2023
accepted: 13 11 2023
medline: 29 12 2023
pubmed: 29 12 2023
entrez: 29 12 2023
Statut: epublish

Résumé

Donor proteinuria (DP) is a common but rarely evaluated aspect of today's kidney transplant allocation process. While proteinuria after kidney transplantation is a risk factor for impaired graft function and survival, the long-term effects of DP in kidney transplantation have not yet been evaluated. Therefore, this study aims to investigate the impact of DP on the long-term outcome after kidney transplantation. A total of 587 patients were found to be eligible and were stratified into two groups: (1) those receiving a graft from a donor without proteinuria (DP-) and (2) those receiving a graft from a donor with proteinuria (DP+). At 36 months, there was no difference in the primary composite endpoint including graft loss and patient survival (log-rank test,

Identifiants

pubmed: 38156296
doi: 10.3389/ti.2023.11953
pii: 11953
pmc: PMC10754218
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

11953

Informations de copyright

Copyright © 2023 Pollmann, Vogel, Pongs, Katou, Morgül, Houben, Görlich, Kneifel, Reuter, Pollmann, Pascher and Becker.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Auteurs

Nicola Sariye Pollmann (NS)

Department of General, Visceral and Transplant Surgery, University Hospital Muenster, Muenster, Germany.

Thomas Vogel (T)

Department of General, Visceral and Transplant Surgery, University Hospital Muenster, Muenster, Germany.

Caroline Pongs (C)

Department of General, Visceral and Transplant Surgery, University Hospital Muenster, Muenster, Germany.

Shadi Katou (S)

Department of General, Visceral and Transplant Surgery, University Hospital Muenster, Muenster, Germany.

Haluk Morgül (H)

Department of General, Visceral and Transplant Surgery, University Hospital Muenster, Muenster, Germany.

Philipp Houben (P)

Department of General, Visceral and Transplant Surgery, University Hospital Muenster, Muenster, Germany.

Dennis Görlich (D)

Institute of Biostatistics and Clinical Research, University Hospital Muenster, Muenster, Germany.

Felicia Kneifel (F)

Department of General, Visceral and Transplant Surgery, University Hospital Muenster, Muenster, Germany.

Stefan Reuter (S)

Department of Medicine D, Division of General Internal Medicine, Nephrology and Rheumatology, University Hospital Muenster, Muenster, Germany.

Lukas Pollmann (L)

Department of General, Visceral and Transplant Surgery, University Hospital Muenster, Muenster, Germany.

Andreas Pascher (A)

Department of General, Visceral and Transplant Surgery, University Hospital Muenster, Muenster, Germany.

Felix Becker (F)

Department of General, Visceral and Transplant Surgery, University Hospital Muenster, Muenster, Germany.

Classifications MeSH