Regional assessment of availability for transcatheter aortic valve implantation in Sweden: a long-term observational study.

Aortic stenosis Equal care, Implementation Health care organisation Transcatheter aortic valve implantation

Journal

European heart journal. Quality of care & clinical outcomes
ISSN: 2058-1742
Titre abrégé: Eur Heart J Qual Care Clin Outcomes
Pays: England
ID NLM: 101677796

Informations de publication

Date de publication:
29 Dec 2023
Historique:
medline: 2 1 2024
pubmed: 2 1 2024
entrez: 29 12 2023
Statut: aheadofprint

Résumé

Transcatheter aortic valve implantation (TAVI) is an increasingly important treatment option for patients with severe aortic stenosis. Its best implementation is debated, as few centres with high volumes are associated with better outcomes, while centralisation might lead to an inferior availability of treatment for patients living far away. The aim of this study was to investigate the implementation of TAVI in Sweden with a focus on regional differences in terms of availability, short-term mortality and waiting times. All patients undergoing TAVI between 2008 and 2020 from the Swedish Transcatheter Cardiac Intervention Registry (SWENTRY) were included. SWENTRY was linked to the National Cause of Death Registry and to publicly available geospatial data from Statistics Sweden. A total of 7280 patients were included. Over time, TAVI interventions increased markedly, while surgical aortic valve replacement (SAVR) remained constant. There were no statistically significant regional differences in incidence between counties with or without a local TAVI centre (p = 0.7) and no clustering tendencies around regions with a local TAVI centre (p = 0.99). Thirty-day mortality improved over time without evidence of regional differences. No regional differences in waiting time from decision to intervention were found for TAVI centre regions and non-TAVI centre regions (p = 0.7). This nationwide study indicated no regional differences in terms of availability, short-term mortality or waiting times. An organisation with a few specialised centres was found to be sufficient to provide national coverage of TAVI interventions.

Sections du résumé

BACKGROUND BACKGROUND
Transcatheter aortic valve implantation (TAVI) is an increasingly important treatment option for patients with severe aortic stenosis. Its best implementation is debated, as few centres with high volumes are associated with better outcomes, while centralisation might lead to an inferior availability of treatment for patients living far away. The aim of this study was to investigate the implementation of TAVI in Sweden with a focus on regional differences in terms of availability, short-term mortality and waiting times.
METHODS METHODS
All patients undergoing TAVI between 2008 and 2020 from the Swedish Transcatheter Cardiac Intervention Registry (SWENTRY) were included. SWENTRY was linked to the National Cause of Death Registry and to publicly available geospatial data from Statistics Sweden.
RESULTS RESULTS
A total of 7280 patients were included. Over time, TAVI interventions increased markedly, while surgical aortic valve replacement (SAVR) remained constant. There were no statistically significant regional differences in incidence between counties with or without a local TAVI centre (p = 0.7) and no clustering tendencies around regions with a local TAVI centre (p = 0.99). Thirty-day mortality improved over time without evidence of regional differences. No regional differences in waiting time from decision to intervention were found for TAVI centre regions and non-TAVI centre regions (p = 0.7).
CONCLUSION CONCLUSIONS
This nationwide study indicated no regional differences in terms of availability, short-term mortality or waiting times. An organisation with a few specialised centres was found to be sufficient to provide national coverage of TAVI interventions.

Identifiants

pubmed: 38158216
pii: 7503921
doi: 10.1093/ehjqcco/qcad076
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology.

Auteurs

Konrad Nilsson (K)

Department of Medical Sciences, Cardiology, Uppsala Universitet, Uppsala, Sweden.
Department of Medicine, Visby Lasarett, Visby, Sweden.

Daniel Lindholm (D)

Department of Medical Sciences, Epidemiology, Uppsala Universitet, Uppsala, Sweden.
Department of Medicine, Norrtälje Hospital (TioHundra AB), Norrtälje, Sweden.

Jenny Backes (J)

Department of Medical Sciences, Örebro Universitet, Örebro, Sweden.

Henrik Bjursten (H)

Department of Cardiothoracic Surgery, Anaesthesia and Intensive Care, Lund University/Skåne University Hospital, Lund, Sweden.

Henrik Hagström (H)

Department of Public Health and Clinical Medicine, Umeå University, and Heart Centre, Umeå University Hospital, Umeå, Sweden.

Johan Lindbäck (J)

Uppsala Clinical Research Center, Uppsala, Sweden.

Pétur Pétursson (P)

Department of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden.

Magnus Settergren (M)

Department of Cardiology, Karolinska Institutet, Stockholm, Sweden.

Giovanna Sarno (G)

Department of Medical Sciences, Cardiology, Uppsala Universitet, Uppsala, Sweden.
Uppsala Clinical Research Center, Uppsala, Sweden.

Stefan James (S)

Department of Medical Sciences, Cardiology, Uppsala Universitet, Uppsala, Sweden.
Uppsala Clinical Research Center, Uppsala, Sweden.

Classifications MeSH