The Role of Hyperdense Basilar Artery Sign in Predicting Outcome of Acute Basilar Artery Occlusion within 12 Hours of Onset.

BACKGROUND

The correlation between hyperdense basilar artery sign (HDBAS) and outcome after acute basilar artery occlusion (ABAO) is debated. Our objective was to determine the usefulness of HDBAS in predicting the outcomes of patients with ABAO after endovascular treatment (EVT), intravenous thrombolysis (IVT), and best medical treatment (BMT).

METHODS

The study's participants were selected from the ATTENTION trial. The study's primary outcome was a 90-day modified Rankin Scale (mRS) score, and the secondary outcome was the recanalization rate, any intracranial hemorrhage, and 90-day mortality.

RESULTS

The study comprised 276 participants, with cohorts for EVT (N=188), IVT (N=82), and BMT (N=88). In EVT cohort, the HDBAS was not associated with 90-day mRS (adjusted OR, 0.87; 95% CI, 0.51-1.48; P=0.6029), the recanalization after 24 hours of onset (adjusted OR, 0.76; 95% CI, 0.30-3.61; P=0.9422), and 90-day mortality (adjusted OR, 0.77; 95% CI, 0.41-1.46; P=0.4238). In IVT cohort, the HDBAS was not associated with 90-day mRS (adjusted OR, 0.69; 95% CI, 0.31-1.56; P=0.3742), the recanalization after 24 hours of onset (adjusted OR, 2.24; 95% CI, 0.47-10.78; P=0.3132), and 90-day mortality (adjusted OR, 0.64; 95% CI, 0.26-1.57; P=0.3264). Similarly, in BMT cohort, the HDBAS was not associated with 90-day mRS (adjusted OR, 1.11; 95% CI, 0.47-2.63; P=0.8152), the recanalization after 24 hours of onset (adjusted OR, 1.27; 95% CI, 0.40-4.02; P=0.6874), and 90-day mortality (adjusted OR, 1.17; 95% CI, 0.46-2.96; P=0.748).

CONCLUSION

The HDBAS may not be a reliable predictor of outcomes for patients with ABAO, regardless of whether they received EVT, IVT, or BMT.

Informations de copyright

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