Alpha and beta spillover in liquid scintillation counting analysis of urine samples.

Emergency response Gross alpha/beta urine bioassay Liquid scintillation counting Spillover

Journal

Journal of radioanalytical and nuclear chemistry
ISSN: 0236-5731
Titre abrégé: J Radioanal Nucl Chem
Pays: Netherlands
ID NLM: 8406474

Informations de publication

Date de publication:
12 Jul 2023
Historique:
pmc-release: 12 07 2024
medline: 2 1 2024
pubmed: 2 1 2024
entrez: 1 1 2024
Statut: ppublish

Résumé

Rapid detection and quantification of gross alpha/beta-emitting radionuclides by liquid scintillation counting (LSC) is vital in guiding response to a nuclear or radiological incidents. Liquid scintillation counters use signal pulse shape to discriminate alpha and beta events in samples but require precise optimization to minimize the spillover, or misclassification, of those events. In this study, samples at varying activity levels were analyzed by LSC to determine the effect of activity level, emitter type, and sample matrix on spillover. Analysis proved a matrix effect and a direct correlation of activity level on spillover percentage for both alpha and beta emitting-nuclides.

Identifiants

pubmed: 38162401
doi: 10.1007/s10967-023-09035-8
pmc: PMC10755725
doi:

Types de publication

Journal Article

Langues

eng

Pagination

3837-3844

Déclaration de conflit d'intérêts

Conflict of interest The authors declare that they have no competing financial interest.

Auteurs

Olga Piraner (O)

Centers for Disease Control and Prevention, National Center for Environmental Health, Division of Laboratory Sciences, Inorganic and Radiation Analytical Toxicology Branch, 4770 Buford Hwy, MS S110-5, Atlanta, GA 30341-3717, USA.

Karlee Eardley (K)

Battelle Memorial Institute, 505 King Avenue, Columbus, OH 43201, USA.

Jonathan Button (J)

Centers for Disease Control and Prevention, National Center for Environmental Health, Division of Laboratory Sciences, Inorganic and Radiation Analytical Toxicology Branch, 4770 Buford Hwy, MS S110-5, Atlanta, GA 30341-3717, USA.

Classifications MeSH