Alpha and beta spillover in liquid scintillation counting analysis of urine samples.
Emergency response
Gross alpha/beta urine bioassay
Liquid scintillation counting
Spillover
Journal
Journal of radioanalytical and nuclear chemistry
ISSN: 0236-5731
Titre abrégé: J Radioanal Nucl Chem
Pays: Netherlands
ID NLM: 8406474
Informations de publication
Date de publication:
12 Jul 2023
12 Jul 2023
Historique:
pmc-release:
12
07
2024
medline:
2
1
2024
pubmed:
2
1
2024
entrez:
1
1
2024
Statut:
ppublish
Résumé
Rapid detection and quantification of gross alpha/beta-emitting radionuclides by liquid scintillation counting (LSC) is vital in guiding response to a nuclear or radiological incidents. Liquid scintillation counters use signal pulse shape to discriminate alpha and beta events in samples but require precise optimization to minimize the spillover, or misclassification, of those events. In this study, samples at varying activity levels were analyzed by LSC to determine the effect of activity level, emitter type, and sample matrix on spillover. Analysis proved a matrix effect and a direct correlation of activity level on spillover percentage for both alpha and beta emitting-nuclides.
Identifiants
pubmed: 38162401
doi: 10.1007/s10967-023-09035-8
pmc: PMC10755725
doi:
Types de publication
Journal Article
Langues
eng
Pagination
3837-3844Déclaration de conflit d'intérêts
Conflict of interest The authors declare that they have no competing financial interest.