A widespread picornavirus affects the hemocytes of the noble pen shell (
RNA virus
RT-PCR
immunosuppression
mass mortality
noble pen shell
Journal
Frontiers in veterinary science
ISSN: 2297-1769
Titre abrégé: Front Vet Sci
Pays: Switzerland
ID NLM: 101666658
Informations de publication
Date de publication:
2023
2023
Historique:
received:
06
08
2023
accepted:
13
11
2023
medline:
2
1
2024
pubmed:
2
1
2024
entrez:
2
1
2024
Statut:
epublish
Résumé
The widespread mass mortality of the noble pen shell ( We sampled In 100% of our samples, ultrastructure revealed the presence of a virus (20 nm diameter) capable of replicating within granulocytes and hyalinocytes, leading to the accumulation of complex vesicles of different dimensions within the cytoplasm. As the PV infection progressed, dead hemocytes, infectious exosomes, and budding of extracellular vesicles were visible, along with endocytic vesicles entering other cells. The THC (total hemocyte count) values observed in both captive (eight animals) (3.5 × 10
Identifiants
pubmed: 38164394
doi: 10.3389/fvets.2023.1273521
pmc: PMC10758234
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1273521Informations de copyright
Copyright © 2023 Carella, Prado, De Vico, Palić, Villari, García-March, Tena-Medialdea, Cortés Melendreras, Giménez-Casalduero, Sigovini and Aceto.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The reviewer IG declared a past co-authorship with the authors FC, DP, GD, JT-M, and JG-M to the handling editor.