Blood pressure variability, central autonomic network dysfunction and cerebral small vessel disease in APOE4 carriers.
Journal
medRxiv : the preprint server for health sciences
Titre abrégé: medRxiv
Pays: United States
ID NLM: 101767986
Informations de publication
Date de publication:
14 Dec 2023
14 Dec 2023
Historique:
medline:
4
1
2024
pubmed:
4
1
2024
entrez:
3
1
2024
Statut:
epublish
Résumé
Increased blood pressure variability (BPV) is a risk factor for cerebral small vessel disease (CSVD) and neurodegeneration, independent of age and average blood pressure, particularly in apolipoprotein E4 ( Independently living older adults (n=70) with no history of stroke or dementia were recruited from the community and underwent 5 minutes of resting beat-to-beat blood pressure monitoring, genetic testing, and brain MRI. Resting BPV, Higher BPV was associated with the presence and extent of CSVD in Older
Sections du résumé
Background
UNASSIGNED
Increased blood pressure variability (BPV) is a risk factor for cerebral small vessel disease (CSVD) and neurodegeneration, independent of age and average blood pressure, particularly in apolipoprotein E4 (
Methods
UNASSIGNED
Independently living older adults (n=70) with no history of stroke or dementia were recruited from the community and underwent 5 minutes of resting beat-to-beat blood pressure monitoring, genetic testing, and brain MRI. Resting BPV,
Results
UNASSIGNED
Higher BPV was associated with the presence and extent of CSVD in
Conclusions
UNASSIGNED
Older
Identifiants
pubmed: 38168394
doi: 10.1101/2023.12.13.23299556
pmc: PMC10760290
pii:
doi:
Types de publication
Preprint
Langues
eng