Weight Loss for Patients with Gout and Concomitant Obesity: A Proof-of-Concept Randomized Trial.
Journal
Arthritis & rheumatology (Hoboken, N.J.)
ISSN: 2326-5205
Titre abrégé: Arthritis Rheumatol
Pays: United States
ID NLM: 101623795
Informations de publication
Date de publication:
02 Jan 2024
02 Jan 2024
Historique:
received:
20
11
2023
accepted:
23
11
2023
medline:
4
1
2024
pubmed:
4
1
2024
entrez:
3
1
2024
Statut:
aheadofprint
Résumé
Despite scarce evidence, guidelines recommend weight loss as management strategy for gout patients. We investigated the effect of an intensive dietary intervention on body weight and clinical measures of gout severity in individuals with obesity and gout. We conducted a 16-week randomized, non-blinded, parallel-group trial in Denmark randomly assigning (1:1) individuals with obesity and gout to a low-energy diet or a control diet. The primary outcome was change in body weight. Key secondary outcomes were changes in serum urate (SU) and visual analogue scale (VAS)-assessed pain and fatigue. Between December 1 An intensive dietary intervention was safe and effectively lowered body weight in obese people with gout, but the weight loss did not directly translate into effects on SU, fatigue and pain. This article is protected by copyright. All rights reserved.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
This article is protected by copyright. All rights reserved.