Interferon regulatory factor 4 plays a pivotal role in the development of aGVHD-associated colitis.

Acute GVHD BACH2 IRF4 T helper cells

Journal

Oncoimmunology
ISSN: 2162-402X
Titre abrégé: Oncoimmunology
Pays: United States
ID NLM: 101570526

Informations de publication

Date de publication:
2024
Historique:
medline: 4 1 2024
pubmed: 4 1 2024
entrez: 3 1 2024
Statut: epublish

Résumé

Interferon regulatory factor 4 (IRF4) is a master transcription factor that regulates T helper cell (Th) differentiation. It interacts with the Basic leucine zipper transcription factor, ATF-like (BATF), depletion of which in CD4

Identifiants

DOI: 10.1080/2162402X.2023.2296712 PMID: 38170159 PMC: PMC10761041
pubmed: 38170159
doi: 10.1080/2162402X.2023.2296712
pii: 2296712
pmc: PMC10761041
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2296712

Informations de copyright

© 2023 The Author(s). Published with license by Taylor & Francis Group, LLC.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest related to this work. E.U. acts as medical advisor of Phialogics and received research funding from Gilead and Bristol-Myers Squibb. R.Z. received honorarium for participation in scientific meetings and advisory boards from Incyte, Mallinckrodt and Novartis.

Auteurs

Jochen T Frueh (JT)

Department of Pediatrics, Experimental Immunology and Cell Therapy, Goethe University Frankfurt, Frankfurt am Main, Germany.
Department of Pediatrics, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.

Julia Campe (J)

Department of Pediatrics, Experimental Immunology and Cell Therapy, Goethe University Frankfurt, Frankfurt am Main, Germany.
Department of Pediatrics, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.

Daniele Yumi Sunaga-Franze (DY)

Genomics Platform, Max Delbrueck Center for Molecular Medicine, Berlin Institute of Health, Berlin, Germany.

Nikita A Verheyden (NA)

Institute for Molecular Medicine, University Hospital, Goethe University Frankfurt, Frankfurt, Germany.
Molecular Immunology, Justus Liebig University Giessen, Giessen, Germany.

Sakhila Ghimire (S)

Hematology and Oncology Department, Medical Clinic 3, University Hospital Regensburg, Regensburg, Germany.

Elisabeth Meedt (E)

Hematology and Oncology Department, Medical Clinic 3, University Hospital Regensburg, Regensburg, Germany.

Denise Haslinger (D)

Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.

Sabine Harenkamp (S)

German Red Cross Blood Service BaWüHe, Frankfurt am Main, Germany.

Daniel Staudenraus (D)

Institute for Microbiology, Philipps University, Marburg, Germany.

Sascha Sauer (S)

Genomics Platform, Max Delbrueck Center for Molecular Medicine, Berlin Institute of Health, Berlin, Germany.

Andreas Kreft (A)

Institute of Pathology, University Medical Center Mainz, Mainz, Germany.

Ralf Schubert (R)

Department of Pediatric Medicine, Division of Pneumology, Allergology, Infectious diseaes und Gastroenterology. Frankfurt am Main, Goethe University Frankfurt, Frankfurt, Germany.

Michael Lohoff (M)

Institute for Microbiology, Philipps University, Marburg, Germany.

Andreas Krueger (A)

Institute for Molecular Medicine, University Hospital, Goethe University Frankfurt, Frankfurt, Germany.
Molecular Immunology, Justus Liebig University Giessen, Giessen, Germany.
Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.

Halvard Bonig (H)

German Red Cross Blood Service BaWüHe, Frankfurt am Main, Germany.
Institute for Transfusion Medicine and Immunohematology, Goethe University, Frankfurt am Main, Germany.

Andreas G Chiocchetti (AG)

Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.

Robert Zeiser (R)

Department of Internal Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Ernst Holler (E)

Hematology and Oncology Department, Medical Clinic 3, University Hospital Regensburg, Regensburg, Germany.

Evelyn Ullrich (E)

Department of Pediatrics, Experimental Immunology and Cell Therapy, Goethe University Frankfurt, Frankfurt am Main, Germany.
Department of Pediatrics, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Institute for Transfusion Medicine and Immunohematology, Goethe University, Frankfurt am Main, Germany.
German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, a partnership between DKFZ, University Hospital Frankfurt, Frankfurt, Germany.
University Cancer Center (UCT), Frankfurt am Main, Germany.
ORCID: 0000-0001-8530-1192

Classifications MeSH