The structural basis for deubiquitination by the fingerless USP-type effector TssM.


Journal

Life science alliance
ISSN: 2575-1077
Titre abrégé: Life Sci Alliance
Pays: United States
ID NLM: 101728869

Informations de publication

Date de publication:
Feb 2024
Historique:
received: 06 10 2023
revised: 28 11 2023
accepted: 29 11 2023
medline: 4 1 2024
pubmed: 4 1 2024
entrez: 3 1 2024
Statut: epublish

Résumé

Intracellular bacteria are threatened by ubiquitin-mediated autophagy, whenever the bacterial surface or enclosing membrane structures become targets of host ubiquitin ligases. As a countermeasure, many intracellular pathogens encode deubiquitinase (DUB) effectors to keep their surfaces free of ubiquitin. Most bacterial DUBs belong to the OTU or CE-clan families. The betaproteobacteria

Identifiants

pubmed: 38170641
pii: 7/2/e202302422
doi: 10.26508/lsa.202302422
pii:
doi:

Banques de données

PDB
['2AYO', '3O65', '3VYP', '4UIC', '6NFR', '3TUR', '1UBQ', '8PZ3', '8Q00']

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2023 Hermanns et al.

Auteurs

Thomas Hermanns (T)

https://ror.org/00rcxh774 Institute for Genetics, University of Cologne, Cologne, Germany t.hermanns@uni-koeln.de.

Matthias Uthoff (M)

https://ror.org/00rcxh774 Institute of Biochemistry, University of Cologne, Cologne, Germany.

Ulrich Baumann (U)

https://ror.org/00rcxh774 Institute of Biochemistry, University of Cologne, Cologne, Germany.

Kay Hofmann (K)

https://ror.org/00rcxh774 Institute for Genetics, University of Cologne, Cologne, Germany.

Classifications MeSH