More May Not be Better: Enhanced Spacecraft Shielding May Exacerbate Cognitive Decrements by Increasing Pion Exposures during Deep Space Exploration.


Journal

Radiation research
ISSN: 1938-5404
Titre abrégé: Radiat Res
Pays: United States
ID NLM: 0401245

Informations de publication

Date de publication:
04 Jan 2024
Historique:
received: 23 11 2023
accepted: 15 12 2023
medline: 4 1 2024
pubmed: 4 1 2024
entrez: 3 1 2024
Statut: aheadofprint

Résumé

The pervasiveness of deep space radiation remains a confounding factor for the transit of humans through our solar system. Spacecraft shielding both protects astronauts but also contributes to absorbed dose through galactic cosmic ray interactions that produce secondary particles. The resultant biological effects drop to a minimum for aluminum shielding around 20 g/cm2 but increase with additional shielding. The present work evaluates for the first time, the impact of secondary pions on central nervous system functionality. The fractional pion dose emanating from thicker shielded spacecraft regions could contribute up to 10% of the total absorbed radiation dose. New results from the Paul Scherrer Institute have revealed that low dose exposures to 150 MeV positive and negative pions, akin to a Mars mission, result in significant, long-lasting cognitive impairments. These surprising findings emphasize the need to carefully evaluate shielding configurations to optimize safe exposure limits for astronauts during deep space travel.

Identifiants

pubmed: 38171489
pii: 498078
doi: 10.1667/RADE-23-00241.1.S1
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024 by Radiation Research Society.

Auteurs

Marie-Catherine Vozenin (MC)

Laboratory of Radiation Oncology, Department of Radiation Oncology, Lausanne University Hospital and University of Lausanne, Switzerland.

Yasaman Alaghband (Y)

Department of Radiation Oncology, University of California, Irvine, California 92697-2695.

Olivia G G Drayson (OGG)

Department of Radiation Oncology, University of California, Irvine, California 92697-2695.

Filippo Piaget (F)

Laboratory of Radiation Oncology, Department of Radiation Oncology, Lausanne University Hospital and University of Lausanne, Switzerland.

Ron Leavitt (R)

Laboratory of Radiation Oncology, Department of Radiation Oncology, Lausanne University Hospital and University of Lausanne, Switzerland.

Barrett D Allen (BD)

Department of Radiation Oncology, University of California, Irvine, California 92697-2695.

Ngoc-Lien Doan (NL)

Department of Radiation Oncology, University of California, Irvine, California 92697-2695.

Tigran Rostomyan (T)

Paul Scherrer Institute (PSI), Villigen, Switzerland.

Alberto Stabilini (A)

Paul Scherrer Institute (PSI), Villigen, Switzerland.

Davide Reggiani (D)

Paul Scherrer Institute (PSI), Villigen, Switzerland.

Wojciech Hajdas (W)

Paul Scherrer Institute (PSI), Villigen, Switzerland.

Eduardo G Yukihara (EG)

Paul Scherrer Institute (PSI), Villigen, Switzerland.

John W Norbury (JW)

NASA Langley Research Center, Hampton, Virginia 23666.

Claude Bailat (C)

Institute of Radiation Physics, Lausanne University Hospital and University of Lausanne, Switzerland.

Laurent Desorgher (L)

Institute of Radiation Physics, Lausanne University Hospital and University of Lausanne, Switzerland.

Janet E Baulch (JE)

Department of Radiation Oncology, University of California, Irvine, California 92697-2695.

Charles L Limoli (CL)

Department of Radiation Oncology, University of California, Irvine, California 92697-2695.

Classifications MeSH