BRAF

BRAF Lynch syndrome colorectal cancer immunohistochemistry

Journal

Histopathology
ISSN: 1365-2559
Titre abrégé: Histopathology
Pays: England
ID NLM: 7704136

Informations de publication

Date de publication:
03 Jan 2024
Historique:
revised: 20 11 2023
received: 12 07 2023
accepted: 18 12 2023
medline: 4 1 2024
pubmed: 4 1 2024
entrez: 4 1 2024
Statut: aheadofprint

Résumé

The Lynch syndrome (LS) screening algorithm requires BRAF testing as a fundamental step to distinguish sporadic from LS-associated colorectal carcinomas (CRC). BRAF testing by immunohistochemistry (IHC) has shown variable results in the literature. Our aim was to analyse concordance between BRAF MisMatch repair (MMR) protein (hMLH1, hPMS2, hMSH2, and hMSH6) and BRAF BRAF

Identifiants

pubmed: 38173291
doi: 10.1111/his.15133
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024 The Authors. Histopathology published by John Wiley & Sons Ltd.

Références

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Auteurs

Federica Grillo (F)

IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Pathology Unit, Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.

Michele Paudice (M)

IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Pathology Unit, Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.

Simona Pigozzi (S)

IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Pathology Unit, Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.

Maria Dono (M)

Molecular Diagnostic Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.

Sonia Lastraioli (S)

Molecular Diagnostic Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.

Marialuisa Lugaresi (M)

Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum, University of Bologna, Bologna, Italy.
Division of Thoracic Surgery, Maria Cecilia Hospital, GVM Care & Research Group, Ravenna, Italy.

Silvia Bozzano (S)

Pathology Unit, Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.

Camilla Tognoni (C)

Pathology Unit, Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.

Murad Ali (M)

Pathology Unit, Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.

Stefania Sciallero (S)

Medical Oncology Unit 1, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.

Alberto Puccini (A)

Medical Oncology and Hematology Unit, Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Milan, Italy.

Matteo Fassan (M)

Surgical Pathology Unit, Department of Medicine (DIMED), University Hospital of Padua, Padua, Italy.
Veneto Institute of Oncology IOV - IRCCS, Padua, Italy.

Luca Mastracci (L)

IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Pathology Unit, Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.

Classifications MeSH