Neutrophil extracellular traps regulating tumorimmunity in hepatocellular carcinoma.

hepatocellular carcinoma (HCC) liver ischemia-reperfusion injury (liver I/R injury) liver transplantation neutrophil extracellular trap (NET) formation tumorigenesis and progression

Journal

Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960

Informations de publication

Date de publication:
2023
Historique:
received: 06 07 2023
accepted: 23 11 2023
medline: 5 1 2024
pubmed: 4 1 2024
entrez: 4 1 2024
Statut: epublish

Résumé

As a component of the innate immune system, there is emerging evidence to suggest that neutrophils may play a critical role in the initiation and progression of hepatocellular carcinoma (HCC). Neutrophil extracellular traps (NETs) are web-like chromatin structures that protrude from the membranes during neutrophil activation. Recent research has shown that NETs, which are at the forefront of the renewed interest in neutrophil studies, are increasingly intertwined with HCC. By exploring the mechanisms of NETs in HCC, we aim to improve our understanding of the role of NETs and gain deeper insights into neutrophil biology. Therefore, this article provides a summary of key findings and discusses the emerging field of NETs in HCC.

Identifiants

pubmed: 38173719
doi: 10.3389/fimmu.2023.1253964
pmc: PMC10764195
doi:

Types de publication

Journal Article Review Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1253964

Informations de copyright

Copyright © 2023 Zhu, Fan, Dong, Li, Chen and Zhou.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Weixiong Zhu (W)

The Second Clinical Medical College, Lanzhou University, Lanzhou, China.
Department of General Surgery, The Second Hospital of Lanzhou University, Lanzhou, China.

Chuanlei Fan (C)

The First Clinical Medical College, Lanzhou University, Lanzhou, China.

Shi Dong (S)

The Second Clinical Medical College, Lanzhou University, Lanzhou, China.
Department of General Surgery, The Second Hospital of Lanzhou University, Lanzhou, China.

Xin Li (X)

The Second Clinical Medical College, Lanzhou University, Lanzhou, China.
The First Clinical Medical College, Lanzhou University, Lanzhou, China.

Haofei Chen (H)

The Second Clinical Medical College, Lanzhou University, Lanzhou, China.
Department of General Surgery, The Second Hospital of Lanzhou University, Lanzhou, China.

Wence Zhou (W)

The Second Clinical Medical College, Lanzhou University, Lanzhou, China.
Department of General Surgery, The Second Hospital of Lanzhou University, Lanzhou, China.

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