Tonic NMDAR currents of NR2A-containing NMDARs represent altered ambient glutamate concentration in the supraoptic nucleus.

Journal

eNeuro
ISSN: 2373-2822
Titre abrégé: eNeuro
Pays: United States
ID NLM: 101647362

Informations de publication

Date de publication:
04 Jan 2024
Historique:
received: 26 07 2023
revised: 03 12 2023
accepted: 21 12 2023
medline: 5 1 2024
pubmed: 5 1 2024
entrez: 4 1 2024
Statut: aheadofprint

Résumé

NMDA receptors (NMDARs) modulate glutamatergic excitatory tone in the brain via two complementary modalities: a phasic excitatory postsynaptic current and a tonic extrasynaptic modality. Here, we demonstrated that the tonic extrasynaptic NMDAR- current (I

Identifiants

DOI: 10.1523/ENEURO.0279-23.2023 PMID: 38176904
pubmed: 38176904
pii: ENEURO.0279-23.2023
doi: 10.1523/ENEURO.0279-23.2023
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2024 Shin et al.

Auteurs

Hyunjin Shin (H)

Department of Medical Sciences, Graduate School, Chungnam National University, Daejeon 35015, Republic of Korea.

Ramesh Sharma (R)

Department of Medical Sciences, Graduate School, Chungnam National University, Daejeon 35015, Republic of Korea.
Laboratory of Veterinary Pharmacology, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 08823, Korea.

Chiranjivi Neupane (C)

Laboratory of Veterinary Pharmacology, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 08823, Korea.

Thuy Linh Pham (TL)

Department of Medical Sciences, Graduate School, Chungnam National University, Daejeon 35015, Republic of Korea.

Su Eun Park (SE)

Department of Medical Sciences, Graduate School, Chungnam National University, Daejeon 35015, Republic of Korea.

So Yeong Lee (SY)

Laboratory of Veterinary Pharmacology, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 08823, Korea.

Hyun-Woo Kim (HW)

Department of Medical Sciences, Graduate School, Chungnam National University, Daejeon 35015, Republic of Korea.

Young Min Bae (YM)

Department of Physiology, Konkuk University, School of Medicine, Seoul 27478, Korea.

Javier E Stern (JE)

Neuroscience Institute and Center for Neuroinflammation and Cardiometabolic Diseases, Georgia State University, Atlanta GA.

Jin Bong Park (JB)

Laboratory of Veterinary Pharmacology, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 08823, Korea. jbpark@snu.ac.kr.

Classifications MeSH