Meeting report of the 4th European Biotransformation Workshop.

AMS F-NMR for metabolite profiling LC-ICP-MS for metabolite profiling Mass Metasite biotransformation softwares unusual biotransformation reactions

Journal

Xenobiotica; the fate of foreign compounds in biological systems
ISSN: 1366-5928
Titre abrégé: Xenobiotica
Pays: England
ID NLM: 1306665

Informations de publication

Date de publication:
04 Jan 2024
Historique:
medline: 5 1 2024
pubmed: 5 1 2024
entrez: 5 1 2024
Statut: aheadofprint

Résumé

Challenges, strategies and new technologies in the field of biotransformation were presented and discussed at the fourth European Biotransformation Workshop which was held in collaboration with the joint ISSX/DMDG meeting on June 15, 2023 at the University of Hertfordshire in Hatfield, UK. In this meeting report we summarise the presentations and discussions from this workshop.The topics covered are listed below:Unusual biotransformation reactionsBiotransformation Workflows in Discovery utilizing various softwares for structure elucidationBiotransformation software for the identification of peptide metabolitesAccelerator Mass Spectrometry (AMS) for endogenous and xenobiotic metabolite profilingMetabolite profiling using quantitative Nuclear magnetic resonance (NMR) and liquid chromatography coupled to inductively coupled plasma-mass spectrometry (LC-ICP-MS).

Identifiants

pubmed: 38178690
doi: 10.1080/00498254.2024.2302547
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-9

Auteurs

M Walles (M)

Pharmacokinetic Sciences, Biomedical Research, Novartis, Basel, Switzerland.

A Pähler (A)

Pharma Research and Early Development, F. Hoffmann-La Roche, Basel, Switzerland.

E M Isin (EM)

DMPK, Translational Medicine, Servier, Paris-Saclay, France.

Marie M Ahlqvist (MM)

Drug Metabolism and Pharmacokinetics, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.

Classifications MeSH