The temporal association between social isolation, distress, and psychotic experiences in individuals at clinical high-risk for psychosis.

clinical high-risk distress experience sampling methodology negative affect psychotic experiences social isolation solitary stress

Journal

Psychological medicine
ISSN: 1469-8978
Titre abrégé: Psychol Med
Pays: England
ID NLM: 1254142

Informations de publication

Date de publication:
05 Jan 2024
Historique:
medline: 5 1 2024
pubmed: 5 1 2024
entrez: 5 1 2024
Statut: aheadofprint

Résumé

Psychotic experiences (PEs) and social isolation (SI) seem related during early stages of psychosis, but the temporal dynamics between the two are not clear. Literature so far suggests a self-perpetuating cycle wherein momentary increases in PEs lead to social withdrawal, which, subsequently, triggers PEs at a next point in time, especially when SI is associated with increased distress. The current study investigated the daily-life temporal associations between SI and PEs, as well as the role of SI-related and general affective distress in individuals at clinical high risk (CHR) for psychosis. We used experience sampling methodology in a sample of 137 CHR participants. We analyzed the association between SI, PEs, and distress using time-lagged linear mixed-effects models. SI did not predict next-moment fluctuations in PEs, or Our results suggest that SI and PEs are not directly related on a moment-to-moment level, but a negative emotional state when alone does contribute to the risk of PEs. These findings highlight the role of affective wellbeing during early-stage psychosis development.

Sections du résumé

BACKGROUND BACKGROUND
Psychotic experiences (PEs) and social isolation (SI) seem related during early stages of psychosis, but the temporal dynamics between the two are not clear. Literature so far suggests a self-perpetuating cycle wherein momentary increases in PEs lead to social withdrawal, which, subsequently, triggers PEs at a next point in time, especially when SI is associated with increased distress. The current study investigated the daily-life temporal associations between SI and PEs, as well as the role of SI-related and general affective distress in individuals at clinical high risk (CHR) for psychosis.
METHODS METHODS
We used experience sampling methodology in a sample of 137 CHR participants. We analyzed the association between SI, PEs, and distress using time-lagged linear mixed-effects models.
RESULTS RESULTS
SI did not predict next-moment fluctuations in PEs, or
CONCLUSIONS CONCLUSIONS
Our results suggest that SI and PEs are not directly related on a moment-to-moment level, but a negative emotional state when alone does contribute to the risk of PEs. These findings highlight the role of affective wellbeing during early-stage psychosis development.

Identifiants

DOI: 10.1017/S0033291723003598 PMID: 38179659
pubmed: 38179659
doi: 10.1017/S0033291723003598
pii: S0033291723003598
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-9

Subventions

Organisme : European Research Council
ID : 309767 - INTERACT
Pays : International

Auteurs

Zeynep Akcaoglu (Z)

Department of Neurosciences, Psychiatry Research Group, Center for Contextual Psychiatry, KU Leuven, Leuven, Belgium.
ORCID: 0000-0002-8619-6301

Thomas Vaessen (T)

Department of Neurosciences, Psychiatry Research Group, Center for Contextual Psychiatry, KU Leuven, Leuven, Belgium.
Department of Psychology, Health & Technology, Faculty of Behavioural, Management and Social Sciences (BMS), University of Twente, Enschede, The Netherlands.
ORCID: 0000-0002-9300-3117

Eva Velthorst (E)

Department of Research, Community Mental Health Service GGZ Noord-Holland-Noord, Heerhugowaard, The Netherlands.

Ginette Lafit (G)

Department of Neurosciences, Psychiatry Research Group, Center for Contextual Psychiatry, KU Leuven, Leuven, Belgium.
Faculty of Psychology and Educational Sciences, Research Group of Quantitative Psychology and Individual Differences, KU Leuven, Leuven, Belgium.

Robin Achterhof (R)

Department of Neurosciences, Psychiatry Research Group, Center for Contextual Psychiatry, KU Leuven, Leuven, Belgium.

Barnaby Nelson (B)

Centre for Youth Mental Health, University of Melbourne, Parkville, Victoria, Australia.
Orygen, The National Centre of Excellence in Youth Mental Health, Melbourne, Victoria, Australia.

Patrick McGorry (P)

Orygen, The National Centre of Excellence in Youth Mental Health, Melbourne, Victoria, Australia.

Frederike Schirmbeck (F)

Department of Psychiatry, Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, North Holland, Netherlands.
Arkin, Institute for Mental Health, Amsterdam, North Holland, The Netherlands.

Craig Morgan (C)

ESRC Centre for Society and Mental Health and Social Epidemiology Research Group, King's College London, London, London, UK.
Health Service and Population Research Department, Centre for Epidemiology and Public Health, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.

Jessica Hartmann (J)

Orygen, The National Centre of Excellence in Youth Mental Health, Melbourne, Victoria, Australia.
Department of Public Mental Health, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Baden-Württemberg, Germany.

Mark van der Gaag (M)

Department of Clinical, Neuro and Developmental Psychology, Vrije Universiteit, Amsterdam, North Holland, The Netherlands.
Department of Psychosis Research, Parnassia Psychiatric Institute, The Hague, South Holland, The Netherlands.

Lieuwe de Haan (L)

Department of Early Psychosis, Amsterdam UMC, Location AMC, Amsterdam, North Holland, The Netherlands.

Lucia Valmaggia (L)

Department of Psychology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
NIHR Biomedical Research Centre, South London and Maudsley NHS Foundation Trust, London, UK.

Philip McGuire (P)

NIHR Biomedical Research Centre, South London and Maudsley NHS Foundation Trust, London, UK.

Matthew Kempton (M)

Department of Psychosis Studies, Institute of Psychiatry, King's Health Partners, King's College London, London, UK.

Henrietta Steinhart (H)

Department of Neurosciences, Psychiatry Research Group, Center for Contextual Psychiatry, KU Leuven, Leuven, Belgium.
Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.

Annelie Klippel (A)

Department of Neurosciences, Psychiatry Research Group, Center for Contextual Psychiatry, KU Leuven, Leuven, Belgium.
Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.
Department of Lifespan Psychology, Faculty of Psychology, Open University, Heerlen, The Netherlands.

Wolfgang Viechtbauer (W)

Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.

Tim Batink (T)

Department of Lifespan Psychology, Faculty of Psychology, Open University, Heerlen, The Netherlands.

Ruud van Winkel (R)

Department of Neurosciences, Psychiatry Research Group, Center for Clinical Psychiatry, KU Leuven, Leuven, Belgium.

Thérèse van Amelsvoort (T)

Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.

Machteld Marcelis (M)

Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.
Institute for Mental Health Care Eindhoven (GGzE), Eindhoven, The Netherlands, https://www.ggze.nl/.

Evelyne van Aubel (E)

Department of Neurosciences, Psychiatry Research Group, Center for Contextual Psychiatry, KU Leuven, Leuven, Belgium.

Ulrich Reininghaus (U)

ESRC Centre for Society and Mental Health and Social Epidemiology Research Group, King's College London, London, London, UK.
Health Service and Population Research Department, Centre for Epidemiology and Public Health, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Department of Public Mental Health, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Baden-Württemberg, Germany.

Inez Myin-Germeys (I)

Department of Neurosciences, Psychiatry Research Group, Center for Contextual Psychiatry, KU Leuven, Leuven, Belgium.

Classifications MeSH