Risk Predictors of Race Disparity in Patients Undergoing Coronary Artery Bypass Grafting. A Propensity Matched Analysis.

CABG CAD Race Risk Factors: Long-Term Outcomes

Journal

Interdisciplinary cardiovascular and thoracic surgery
ISSN: 2753-670X
Titre abrégé: Interdiscip Cardiovasc Thorac Surg
Pays: England
ID NLM: 9918540787006676

Informations de publication

Date de publication:
05 Jan 2024
Historique:
received: 29 08 2023
revised: 25 09 2023
accepted: 04 01 2024
medline: 5 1 2024
pubmed: 5 1 2024
entrez: 5 1 2024
Statut: aheadofprint

Résumé

To compare long-term prognosis after isolated coronary artery bypass grafting (CABG) between white and black patients, and to investigate risk factors for poorer outcomes among the latest. All consecutive 4,766 black and white patients undergoing isolated CABG between 05/2005 and 06/2021 at our institution were included. Primary outcomes were long-term incidence of all-cause death and major adverse cardiovascular and cerebrovascular events in black vs white patients. A propensity-matched analysis was used two compare groups. After matching, 459 patients were included in each black and white groups while groups were correctly balanced. Mean age was 70.4 vs 70.6-year-old (p = 0.7) in black and white groups, respectively. Intraoperatively, mean operating room time and blood product transfusion, were higher in the black group while incidence of extubation in the operating room was higher in the white one. Postoperatively, hospital length of stay was higher in the black cohort. Thirty-day all cause mortality was not different among groups. Median follow-up time was 4-years. Primary outcome of all-cause death was higher in the black vs the white, respectively. Major adverse cardiovascular and cerebrovascular events incidence was twice higher in the black compared to the white cohort (7.6% vs 3.7%, p = 0.013). Risk-predictors for all-cause death and major adverse cardiovascular and cerebrovascular events in blacks were creatinine level, chronic obstructive pulmonary disease, ejection fraction < 50%, and pre-operative atrial fibrillation. Racial disparities persist in a high-volume center. Despite no pre-operative difference, black minority has a higher incidence of major adverse cardiovascular and cerebrovascular events.

Identifiants

pubmed: 38180892
pii: 7511859
doi: 10.1093/icvts/ivae002
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© The Author(s) 2024. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery.

Auteurs

Aleksander Dokollari (A)

Department of Cardiac Surgery Research, Lankenau Institute for Medical Research, Main Line Health, Wynnewood, Pennsylvania, USA.
Department of Cardiac Surgery, Lankenau Heart Institute, Lankenau Medical Center, Main Line Health, Wynnewood, Pennsylvania, USA.

Serge Sicouri (S)

Department of Cardiac Surgery Research, Lankenau Institute for Medical Research, Main Line Health, Wynnewood, Pennsylvania, USA.

Basel Ramlawi (B)

Department of Cardiac Surgery Research, Lankenau Institute for Medical Research, Main Line Health, Wynnewood, Pennsylvania, USA.
Department of Cardiac Surgery, Lankenau Heart Institute, Lankenau Medical Center, Main Line Health, Wynnewood, Pennsylvania, USA.

Rakesh C Arora (RC)

Department of Cardiac Surgery, Cleveland Clinic, Ohio, USA.

Daniel Lodge (D)

Penn State Health, University of Pennsylvania, Pennsylvania, USA.

Kelly M Wanamaker (KM)

Department of Cardiac Surgery, Baystate Medical Center, Springfield, MA, USA.

Leila Hosseinian (L)

Department of Cardiac Surgery, Lankenau Heart Institute, Lankenau Medical Center, Main Line Health, Wynnewood, Pennsylvania, USA.

Ozgun Erten (O)

Department of Cardiac Surgery Research, Lankenau Institute for Medical Research, Main Line Health, Wynnewood, Pennsylvania, USA.

Gianluca Torregrossa (G)

Department of Cardiac Surgery Research, Lankenau Institute for Medical Research, Main Line Health, Wynnewood, Pennsylvania, USA.
Department of Cardiac Surgery, Lankenau Heart Institute, Lankenau Medical Center, Main Line Health, Wynnewood, Pennsylvania, USA.

Francis P Sutter (FP)

Department of Cardiac Surgery, Lankenau Heart Institute, Lankenau Medical Center, Main Line Health, Wynnewood, Pennsylvania, USA.

Classifications MeSH