The habits of European urologists in the field of cryopreservation before the urological cancers treatment.
bladder cancer
male fertility
prostate cancer
testicular cancer
Journal
Andrology
ISSN: 2047-2927
Titre abrégé: Andrology
Pays: England
ID NLM: 101585129
Informations de publication
Date de publication:
06 Jan 2024
06 Jan 2024
Historique:
revised:
24
10
2023
received:
16
05
2023
accepted:
11
12
2023
medline:
7
1
2024
pubmed:
7
1
2024
entrez:
6
1
2024
Statut:
aheadofprint
Résumé
Treatments against urogenital cancers frequently have fertility side-effects. The strategy to preserve fertility after oncologic treatments is still a matter of debate with a lack of evidence and international guidelines. The aim of this study is to investigate fertility preservation practices before urogenital cancer treatments and to compare national habits. An online anonymous survey was submitted from January to June 2021 to six European urological societies. The 31-items questionnaire included questions about demography, habits of evaluation, and management of fertility preservation in case of urogenital cancer treatments. Two hundred twenty-eight urologists from six urological societies in five different countries (Belgium, The Netherlands, Luxembourg, France, Finland) filled out the survey. Three quarter (74%; n = 166) usually propose a cryopreservation before orchidectomy. In case of oligo/azoo-spermia, the technique performed for the sperm extraction during orchidectomy varies among the sample: 70.5% (n = 160) of the responders do not perform a Testicular Sperm Extraction (TESE) nor a Percutaneous Epididymal Sperm Aspiration (PESA). The cryopreservation for prostate cancer treatments is never proposed in 48.17% (n = 105) of responders but conversely it is always proposed in 5.05% (n = 11). The cryopreservation before bladder cancer treatments is not commonly proposed (67.5%, n = 154). Our study showed variable country specific tendencies in terms of fertility preservation in the period of treatment of urological cancers. These differences seem to be related to national guidelines recommendations. Standardization of international guidelines is urgently needed in the field of fertility for urological cancer patients.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2024 American Society of Andrology and European Academy of Andrology.
Références
Trottmann M, Becker AJ, Stadler T, et al. Semen quality in men with malignant diseases before and after therapy and the role of cryopreservation. Eur Urol. 2007;52(2):355-367.
Matos E, Skrbinc B, Zakotnik B. Fertility in patients treated for testicular cancer. J Cancer Surviv. 2010;4(3):274-278.
Suzuki K, Yumura Y, Ogawa T, Saito K, Kinoshita Y, Noguchi K. Regeneration of spermatogenesis after testicular cancer chemotherapy. Urol Int. 2013;91(4):445-450.
Ferrari S, Paffoni A, Filippi F, Busnelli A, Vegetti W, Somigliana E. Sperm cryopreservation and reproductive outcome in male cancer patients: a systematic review. Reprod Biomed Online. 2016;33(1):29-38.
Loren AW, Mangu PB, Beck LN, et al. Fertility preservation for patients with cancer: American Society of Clinical Oncology clinical practice guideline update. J Clin Oncol. 2013;31(19):2500-2510.
Ferrari S, Paffoni A, Reschini M, et al. Variables affecting long-term usage rate of sperm samples cryopreserved for fertility preservation in cancer patients. Andrology. 2021;9(1):204-211.
Laguna MP, Pizzocaro G, Klepp O, Algaba F, Kisbenedek L, Leiva O. EAU guidelines on testicular cancer. Eur Urol. 2001;40(2):102-110.
Patrikidou A, Cazzaniga W, Berney D, et al. European Association of Urology Guidelines on Testicular Cancer: 2023 Update. Eur Urol. 2023;84(3):289-301. doi:10.1016/j.eururo.2023.04.010
Degraeve A, Roumeguere T, Tilmans G, et al. Société Belge d'Urologie (SBU), the Belgische Vereniging voor Urologen (BVU), the Association Française d'Urologie (AFU), the Nederlandse Vereniging voor Urologie (NVU), the Société d'Andrologie de Langue Française (SALF), the Finnish Urological Society (FUS). European countries have different rates of sperm cryopreservation before vasectomy and at the time of reversal. Andrology. 2022;10(7):1286-1291. doi:10.1111/andr.13182
Emmanuel A, Kanthabalan A, Alexander C, et al. Expedited radical orchidectomy for testicular cancer: compromising fertility outcomes without oncological benefit? Eur Urol. 2021;80(6):766-767.
Ferlin A, Calogero AE, Krausz C, et al. Management of male factor infertility: position statement from the Italian Society of Andrology and Sexual Medicine (SIAMS): endorsing organization: Italian Society of Embryology, Reproduction, and Research (SIERR). J Endocrinol Invest. 2022;45(5):1085-1113.
Walschaerts M, Bujan L, Chouquet C, Rossi V, Juillard JC, Thonneau P. Sperm cryopreservation incidence in men with testicular cancer: towards a stabilization in testicular cancer incidence? Results from the CECOS network. Basic Clin Androl. 2018;28:11.
Murez T, Fléchon A, Branger N, et al. French AFU Cancer Committee Guidelines-Update 2022-2024: testicular germ cell cancer. Prog Urol. 2022;32(15):1066-1101.
Nederlandse Vereniging voor Urologie. Kwaliteitsnormen testiscarcinoom. Versie 3. 2017. https://www.nvu.nl/kwaliteitsbeleid/kwaliteitsnormen/
Walsh TJ, Croughan MS, Schembri M, Chan JM, Turek PJ. Increased risk of testicular germ cell cancer among infertile men. Arch Intern Med. 2009;169(4):351-356.
Rives N, Perdrix A, Hennebicq S, et al. The semen quality of 1158 men with testicular cancer at the time of cryopreservation: results of the French National CECOS Network. J Androl. 2012;33(6):1394-1401.
Jacobsen KD, Fosså SD, Bjøro TP, Aass N, Heilo A, Stenwig AE. Gonadal function and fertility in patients with bilateral testicular germ cell malignancy. Eur Urol. 2002;42(3):229-238. discussion 37-8.
Ostrowski KA, Walsh TJ. Infertility with testicular cancer. Urol Clin North Am. 2015;42(3):409-420.
Moody JA, Ahmed K, Yap T, Minhas S, Shabbir M. Fertility managment in testicular cancer: the need to establish a standardized and evidence-based patient-centric pathway. BJU Int. 2019;123(1):160-172.
Blecher GA, Chung E, Katz D, Kim SHK, Bailie J. Onco-Testicular Sperm Extraction (oncoTESE): a contemporary concept review and report of Australian sperm retrieval rates and fertility outcomes. Urology. 2022;160:109-116.
Sullivan R, Mieusset R. The human epididymis: its function in sperm maturation. Hum Reprod Update. 2016;22(5):574-587.
Záková J, Lousová E, Ventruba P, et al. Sperm cryopreservation before testicular cancer treatment and its subsequent utilization for the treatment of infertility. Sci World J. 2014;2014:575978.
Drechsel KCE, Pilon MCF, Stoutjesdijk F, et al. Reproductive ability in survivors of childhood, adolescent, and young adult Hodgkin lymphoma: a review. Hum Reprod Update. 2023;29(4):486-517.
Zacchini F, Sampino S, Ziętek M, Chan A. Delayed parenthood and its influence on offspring health: what have we learned from the mouse model†. Biol Reprod. 2022;106(1):58-65.
Statbel La Belgique en chiffres. Une mere a en moyenne 31 ans à la naissance de son enfant. 2021.