Vitamin D Levels as a Potential Modifier of Eosinophilic Esophagitis Severity in Adults.

Endoscopy Eosinophils Esophagitis Vitamin D Vitamin D Deficiency

Journal

Digestive diseases and sciences
ISSN: 1573-2568
Titre abrégé: Dig Dis Sci
Pays: United States
ID NLM: 7902782

Informations de publication

Date de publication:
06 Jan 2024
Historique:
received: 02 10 2023
accepted: 27 11 2023
medline: 7 1 2024
pubmed: 7 1 2024
entrez: 6 1 2024
Statut: aheadofprint

Résumé

Vitamin D deficiency is associated with atopic and immune-mediated diseases but has not been extensively assessed in eosinophilic esophagitis (EoE). We aimed to assess if vitamin D levels in newly diagnosed EoE patients were lower than in non-EoE controls and examine levels in relation to EoE clinical features. This secondary analysis of a prospective cohort study used data and biosamples from adults who underwent outpatient esophagogastroduodenoscopy. Before each procedure, blood was obtained and stored at -80 We analyzed 40 EoE and 40 non-EoE controls. Mean serum 25(OH)D After adjusting for age, sex, and race, 25(OH)D

Sections du résumé

BACKGROUND BACKGROUND
Vitamin D deficiency is associated with atopic and immune-mediated diseases but has not been extensively assessed in eosinophilic esophagitis (EoE). We aimed to assess if vitamin D levels in newly diagnosed EoE patients were lower than in non-EoE controls and examine levels in relation to EoE clinical features.
METHODS METHODS
This secondary analysis of a prospective cohort study used data and biosamples from adults who underwent outpatient esophagogastroduodenoscopy. Before each procedure, blood was obtained and stored at -80
RESULTS RESULTS
We analyzed 40 EoE and 40 non-EoE controls. Mean serum 25(OH)D
CONCLUSIONS CONCLUSIONS
After adjusting for age, sex, and race, 25(OH)D

Identifiants

DOI: 10.1007/s10620-023-08264-x PMID: 38183560
pubmed: 38183560
doi: 10.1007/s10620-023-08264-x
pii: 10.1007/s10620-023-08264-x
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NIH HHS
ID : T35 DK007386
Pays : United States
Organisme : NIH HHS
ID : P30 DK034987
Pays : United States

Informations de copyright

© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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Auteurs

Brenderia A Cameron (BA)

Center for Esophageal Diseases and Swallowing, University of North Carolina School of Medicine, CB#7080 Bioinformatics Building 130 Mason Farm Rd. UNC-CH, Chapel Hill, NC, 27599-7080, USA.

Carlton W Anderson (CW)

Center for Gastrointestinal Biology and Disease, Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, USA.

Elizabeth T Jensen (ET)

Center for Esophageal Diseases and Swallowing, University of North Carolina School of Medicine, CB#7080 Bioinformatics Building 130 Mason Farm Rd. UNC-CH, Chapel Hill, NC, 27599-7080, USA.
Department of Epidemiology and Prevention, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Department of Internal Medicine, Gastroenterology Section, Wake Forest University School of Medicine, Winston-Salem, NC, USA.

Evan S Dellon (ES)

Center for Esophageal Diseases and Swallowing, University of North Carolina School of Medicine, CB#7080 Bioinformatics Building 130 Mason Farm Rd. UNC-CH, Chapel Hill, NC, 27599-7080, USA. edellon@med.unc.edu.
Center for Gastrointestinal Biology and Disease, Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, USA. edellon@med.unc.edu.
ORCID: 0000-0003-1167-1101

Classifications MeSH