Durability of deep transcranial magnetic stimulation for veterans with treatment resistant depression with comorbid suicide risk and PTSD symptoms.

Hesed coil Major depressive disorder Posttraumatic stress disorder Suicidal ideation Transcranial magnetic stimulation Treatment resistant depression Veterans dTMS

Journal

Psychiatry research
ISSN: 1872-7123
Titre abrégé: Psychiatry Res
Pays: Ireland
ID NLM: 7911385

Informations de publication

Date de publication:
23 Dec 2023
Historique:
received: 14 08 2023
revised: 20 12 2023
accepted: 21 12 2023
medline: 7 1 2024
pubmed: 7 1 2024
entrez: 6 1 2024
Statut: aheadofprint

Résumé

Evidence supports transcranial magnetic stimulation (TMS) as an effective treatment for symptoms of depression and PTSD; however, there has been limited investigation into the durability of symptoms reduction. The Hampton Veterans Affairs Medical Center's (HVAMC) rTMS clinic used H-coil for dTMS for Veterans with treatment-resistant depression and tracked symptomology at multiple times points up to six months post-treatment. Veterans underwent 30 session of dTMS treatment using the Hesed coil (H1 coil). The PHQ-9, PCL-5, and BSS were administered to Veterans at four time points: pretreatment, post-treatment, three months after treatment, and six months after treatment. In aggregate, there were clinically significant reductions in symptoms of depression (43.47%), PTSD (44.14%) and suicidal ideation (54.02%) at the six month follow-up relative to pretreatment. Results provide evidence of the impact and durability of dTMS on symptoms of MDD, PTSD, and suicidal ideation among Veterans with treatment-resistant depression.

Identifiants

pubmed: 38183924
pii: S0165-1781(23)00640-6
doi: 10.1016/j.psychres.2023.115690
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

115690

Informations de copyright

Published by Elsevier B.V.

Déclaration de conflit d'intérêts

Declaration of competing interest None.

Auteurs

Robert Hickson (R)

Department of Psychology, Palo Alto University, Palo Alto, CA, United States; VA Palo Alto Health Care System Sierra Pacific Mental Illness Research Education Clinical Center, Palo Alto, CA, United States.

Max W Simonsen (MW)

Hampton VA Medical Center, Hampton, VA, United States; Department of Psychiatry, Eastern Virginia Medical School, Norfolk, VA, United States.

Kenneth J Miller (KJ)

Hampton VA Medical Center, Hampton, VA, United States; Department of Psychiatry, Eastern Virginia Medical School, Norfolk, VA, United States.

Michelle R Madore (MR)

VA Palo Alto Health Care System Sierra Pacific Mental Illness Research Education Clinical Center, Palo Alto, CA, United States; Department of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Stanford, CA, United States. Electronic address: mmadore@stanford.edu.

Classifications MeSH