Full Mass Range ΦSDM Orbitrap Mass Spectrometry for DIA Proteome Analysis.

Orbitrap data-independent acquisition high-throughput proteomics ΦSDM

Journal

Molecular & cellular proteomics : MCP
ISSN: 1535-9484
Titre abrégé: Mol Cell Proteomics
Pays: United States
ID NLM: 101125647

Informations de publication

Date de publication:
04 Jan 2024
Historique:
received: 30 08 2023
revised: 21 12 2023
accepted: 03 01 2024
medline: 7 1 2024
pubmed: 7 1 2024
entrez: 6 1 2024
Statut: aheadofprint

Résumé

Optimizing data-independent acquisition (DIA) methods for proteomics applications often requires balancing spectral resolution and acquisition speed. Here we describe a real-time, full mass range implementation of the Phase-constrained Spectrum Deconvolution Method (ΦSDM) for Orbitrap

Identifiants

pubmed: 38184013
pii: S1535-9476(24)00003-3
doi: 10.1016/j.mcpro.2024.100713
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

100713

Informations de copyright

Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflict of interest The authors declare the following competing financial interest(s): K.F., A.K., D.M.M., K.A., D.G. and A.M. are employees of Thermo Fisher Scientific, the manufacturer of Orbitrap instrumentation used in this research. M. M. is an indirect investor in Evosep Biosystems.

Auteurs

Sophia Steigerwald (S)

Department Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.

Ankit Sinha (A)

Department Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.

Kyle L Fort (KL)

Thermo Fisher Scientific (GmbH) Bremen, Germany.

Wen-Feng Zeng (WF)

Department Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.

Lili Niu (L)

NNF Center for Protein Research University of Copenhagen, Copenhagen, Denmark.

Christoph Wichmann (C)

Department Computational Systems Biochemistry, Max Planck Institute of Biochemistry, Martinsried, Germany.

Arne Kreutzmann (A)

Thermo Fisher Scientific (GmbH) Bremen, Germany.

Daniel Mourad (D)

Thermo Fisher Scientific (GmbH) Bremen, Germany.

Konstantin Aizikov (K)

Thermo Fisher Scientific (GmbH) Bremen, Germany.

Dmitry Grinfeld (D)

Thermo Fisher Scientific (GmbH) Bremen, Germany.

Alexander Makarov (A)

Thermo Fisher Scientific (GmbH) Bremen, Germany.

Matthias Mann (M)

Department Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany; NNF Center for Protein Research University of Copenhagen, Copenhagen, Denmark.

Florian Meier (F)

Department Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany; Functional Proteomics, Jena University Hospital, Jena, Germany.

Classifications MeSH