An Update on Alopecia and its Association With Thyroid Autoimmune Diseases.

Alopecia is comorbid with several illnesses, including various autoimmune conditions such as thyroid disease. Leukocyte-mediated inflammation of hair follicles in alopecia was first described over a century ago. However, the high prevalence of the role of thyroid autoimmune disease in the pathogenesis of alopecia has only recently come to light, together with a strong association between the two. Therefore, this review focuses on articles published between 2011 and 2022 on alopecia's association with thyroid autoimmune disease, and the mechanism behind it. In addition, it highlights the link between alopecia and thyroid cancer, as patients with alopecia have increased risk of thyroid cancer. In conclusion, this comprehensive, focused, scoping review will serve as a reference highlighting recent information on alopecia, exploring its association with thyroid autoimmune diseases.

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Disclosures: Doaa Aboalola, Sihem Aouabdi, Majed Ramadan, Tariq Alghamdi, Mona Alsolami, Dalal Malibari and Rawiah Alsiary have no financial or non-financial relationships or activities to declare in relation to this article.