A single-domain protein catenane of dihydrofolate reductase.

DHFR catenane cellular synthesis chemical topology protein domain

Journal

National science review
ISSN: 2053-714X
Titre abrégé: Natl Sci Rev
Pays: China
ID NLM: 101633095

Informations de publication

Date de publication:
Nov 2023
Historique:
received: 09 03 2023
revised: 07 08 2023
accepted: 07 08 2023
medline: 8 1 2024
pubmed: 8 1 2024
entrez: 8 1 2024
Statut: epublish

Résumé

A single-domain protein catenane refers to two mechanically interlocked polypeptide rings that fold synergistically into a compact and integrated structure, which is extremely rare in nature. Here, we report a single-domain protein catenane of dihydrofolate reductase (

Identifiants

DOI: 10.1093/nsr/nwad304 PMID: 38188024 PMC: PMC10769465
pubmed: 38188024
doi: 10.1093/nsr/nwad304
pii: nwad304
pmc: PMC10769465
doi:

Types de publication

Journal Article

Langues

eng

Pagination

nwad304

Informations de copyright

© The Author(s) 2023. Published by Oxford University Press on behalf of China Science Publishing & Media Ltd.

Auteurs

Jing Fang (J)

Beijing National Laboratory for Molecular Sciences, Key Laboratory of Polymer Chemistry & Physics of Ministry of Education, Center for Soft Matter Science and Engineering, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.

Tianzuo Li (T)

Beijing National Laboratory for Molecular Sciences, Key Laboratory of Polymer Chemistry & Physics of Ministry of Education, Center for Soft Matter Science and Engineering, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.

Jiyeon Lee (J)

Department of Chemistry, Pohang University of Science and Technology (POSTECH), Pohang 37673, Republic of Korea.

Dahye Im (D)

Department of Chemistry, Pohang University of Science and Technology (POSTECH), Pohang 37673, Republic of Korea.

Lianjie Xu (L)

Beijing National Laboratory for Molecular Sciences, Key Laboratory of Polymer Chemistry & Physics of Ministry of Education, Center for Soft Matter Science and Engineering, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.

Yajie Liu (Y)

Beijing National Laboratory for Molecular Sciences, Key Laboratory of Polymer Chemistry & Physics of Ministry of Education, Center for Soft Matter Science and Engineering, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.

Jongcheol Seo (J)

Department of Chemistry, Pohang University of Science and Technology (POSTECH), Pohang 37673, Republic of Korea.

Wen-Bin Zhang (WB)

Beijing National Laboratory for Molecular Sciences, Key Laboratory of Polymer Chemistry & Physics of Ministry of Education, Center for Soft Matter Science and Engineering, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.
Beijing Academy of Artificial Intelligence, Beijing 100084, China.
ORCID: 0000-0002-8746-0792

Classifications MeSH