Tunable theranostics: innovative strategies in combating oral cancer.

Carbon nanotubes Dendrimers Magnetic nanoparticles Microneedles Oral cancer Quantum dots Theranostics

Journal

PeerJ
ISSN: 2167-8359
Titre abrégé: PeerJ
Pays: United States
ID NLM: 101603425

Informations de publication

Date de publication:
2024
Historique:
received: 19 07 2023
accepted: 06 12 2023
medline: 8 1 2024
pubmed: 8 1 2024
entrez: 8 1 2024
Statut: epublish

Résumé

This study aims to assess and compare the potential of advanced nano/micro delivery systems, including quantum dots, carbon nanotubes, magnetic nanoparticles, dendrimers, and microneedles, as theranostic platforms for oral cancer. Furthermore, we seek to evaluate their respective advantages and disadvantages over the past decade. A comprehensive literature search was performed using Google Scholar and PubMed, with a focus on articles published between 2013 and 2023. Search queries included the specific advanced delivery system as the primary term, followed by oral cancer as the secondary term ( The advanced delivery platforms exhibited notable diagnostic and therapeutic advantages when compared to conventional techniques or control groups. These benefits encompassed improved tumor detection and visualization, enhanced precision in targeting tumors with reduced harm to neighboring tissues, and improved drug solubility and distribution, leading to enhanced drug absorption and tumor uptake. The findings suggest that advanced nano/micro delivery platforms hold promise for addressing numerous challenges associated with chemotherapy. By enabling precise targeting of cancerous cells, these platforms have the potential to mitigate adverse effects on surrounding healthy tissues, thus encouraging the development of innovative diagnostic and therapeutic strategies for oral cancer.

Identifiants

pubmed: 38188167
doi: 10.7717/peerj.16732
pii: 16732
pmc: PMC10771769
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e16732

Informations de copyright

©2024 Uthman et al.

Déclaration de conflit d'intérêts

The authors declare there are no competing interests.

Auteurs

Asmaa Uthman (A)

Department of Diagnostic and Surgical Dental Sciences, College of Dentistry, Gulf Medical University, Ajman, United Arab Emirates.

Noor Al-Rawi (N)

Department of Pharmaceutics and Pharmaceutical Technology, University of Sharjah, Sharjah, United Arab Emirates.

Musab Hamed Saeed (MH)

Department of Clinical Sciences, College of Dentistry, Ajman University, Ajman, United Arab Emirates.
Ajman University, Centre of Medical and Bio-allied Health Sciences Research,, Ajman, United Arab Emirates.

Bassem Eid (B)

Department of Restorative Dental Sciences, College of Dentistry, Gulf Medical University, Ajman, Ajman, United Arab Emirates.

Natheer H Al-Rawi (NH)

University of Sharjah, Sharjah Institute of Medical Research, Sharjah, United Arab Emirates.
Department of Oral and Craniofacial Health Sciences, College of Dental Medicine, University of Sharjah, Sharjah, United Arab Emirates.

Classifications MeSH