Hepatoprotective Activity and Mechanisms of Prenylated Stilbenoids.

4-C-geranyl oxyresveratrol SIRT1 bioactivity resveratrol structure

Journal

Journal of agricultural and food chemistry
ISSN: 1520-5118
Titre abrégé: J Agric Food Chem
Pays: United States
ID NLM: 0374755

Informations de publication

Date de publication:
08 Jan 2024
Historique:
medline: 8 1 2024
pubmed: 8 1 2024
entrez: 8 1 2024
Statut: aheadofprint

Résumé

Dietary prenylated stilbenoids, found in various food sources, offer multiple health benefits, including liver protection. However, the underlying mechanisms of hepatoprotection remain unclear. In this study, we synthesized 13 natural prenylated stilbenoids and examined their hepatoprotective activities, with silent mating type information regulation 2 homologue-1 (SIRT1) as the primary target for screening. Among all of the prenylated stilbenoids tested, 4-

Identifiants

DOI: 10.1021/acs.jafc.3c09515 PMID: 38189644
pubmed: 38189644
doi: 10.1021/acs.jafc.3c09515
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Bailin Li (B)

Key State Laboratory of Plant Diversity and Specialty Crops, Guangdong Provincial Key Laboratory of Applied Botany, Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China.
South China National Botanical Garden, Guangzhou 510650, China.
University of Chinese Academy of Sciences, Beijing 100049, China.

Shengtao Bo (S)

Zhaoqing Public Security Judicial Appraisal Center, Zhaoqing 526000, China.
ORCID: 0000-0001-5234-8074

Zhili Sheng (Z)

Key State Laboratory of Plant Diversity and Specialty Crops, Guangdong Provincial Key Laboratory of Applied Botany, Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China.
South China National Botanical Garden, Guangzhou 510650, China.
University of Chinese Academy of Sciences, Beijing 100049, China.

Hong Zhu (H)

Key State Laboratory of Plant Diversity and Specialty Crops, Guangdong Provincial Key Laboratory of Applied Botany, Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China.
South China National Botanical Garden, Guangzhou 510650, China.
University of Chinese Academy of Sciences, Beijing 100049, China.

Yueming Jiang (Y)

Key State Laboratory of Plant Diversity and Specialty Crops, Guangdong Provincial Key Laboratory of Applied Botany, Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China.
South China National Botanical Garden, Guangzhou 510650, China.
University of Chinese Academy of Sciences, Beijing 100049, China.
ORCID: 0000-0002-4648-9572

Bao Yang (B)

Key State Laboratory of Plant Diversity and Specialty Crops, Guangdong Provincial Key Laboratory of Applied Botany, Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China.
South China National Botanical Garden, Guangzhou 510650, China.
University of Chinese Academy of Sciences, Beijing 100049, China.
ORCID: 0000-0002-5483-7960

Classifications MeSH