Contemporary management of major haemorrhage in critical care.
Bleeding
Coagulopathy
Critical illness
Haemorrhage
Massive transfusion
Journal
Intensive care medicine
ISSN: 1432-1238
Titre abrégé: Intensive Care Med
Pays: United States
ID NLM: 7704851
Informations de publication
Date de publication:
Mar 2024
Mar 2024
Historique:
received:
08
09
2023
accepted:
05
12
2023
pubmed:
8
1
2024
medline:
8
1
2024
entrez:
8
1
2024
Statut:
ppublish
Résumé
Haemorrhagic shock is frequent in critical care settings and responsible for a high mortality rate due to multiple organ dysfunction and coagulopathy. The management of critically ill patients with bleeding and shock is complex, and treatment of these patients must be rapid and definitive. The administration of large volumes of blood components leads to major physiological alterations which must be mitigated during and after bleeding. Early recognition of bleeding and coagulopathy, understanding the underlying pathophysiology related to specific disease states, and the development of individualised management protocols are important for optimal outcomes. This review describes the contemporary understanding of the pathophysiology of various types of coagulopathic bleeding; the diagnosis and management of critically ill bleeding patients, including major haemorrhage protocols and post-transfusion management; and finally highlights recent areas of opportunity to better understand optimal management strategies for managing bleeding in the intensive care unit (ICU).
Identifiants
pubmed: 38189930
doi: 10.1007/s00134-023-07303-5
pii: 10.1007/s00134-023-07303-5
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
319-331Subventions
Organisme : Medical Research Council
ID : MR/T023961/1
Pays : United Kingdom
Commentaires et corrections
Type : ErratumIn
Informations de copyright
© 2024. Springer-Verlag GmbH Germany, part of Springer Nature.
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