Lysosome-targeted ruthenium(II) complex encapsulated with pluronic
Antitumor
Cytotoxicity
Lysosomes
Nanoparticles
Oncosis
Ru(II) complexes
Journal
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry
ISSN: 1432-1327
Titre abrégé: J Biol Inorg Chem
Pays: Germany
ID NLM: 9616326
Informations de publication
Date de publication:
08 Jan 2024
08 Jan 2024
Historique:
received:
07
06
2023
accepted:
09
10
2023
medline:
8
1
2024
pubmed:
8
1
2024
entrez:
8
1
2024
Statut:
aheadofprint
Résumé
Transition metal complexes with characteristics of unique packaging in nanoparticles and remarkable cancer cell cytotoxicity have emerged as potential alternatives to platinum-based antitumor drugs. Here we report the synthesis, characterization, and antitumor activities of three new Ruthenium complexes that introduce 5-fluorouracil-derived ligands. Notably, encapsulation of one such metal complex, Ru3, within pluronic
Identifiants
pubmed: 38189962
doi: 10.1007/s00775-023-02039-5
pii: 10.1007/s00775-023-02039-5
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Discipline Construction Project of Guangdong Medical University
ID : 4SG23004G
Organisme : Medical Industry Innovation Project of Guangdong Medical University
ID : 4SG22305P
Organisme : Key Scientific Research Projects of Colleges and Universities in Guangdong Province
ID : 2020ZDZX2031
Organisme : Dongguan Science and Technology of Social Development Program
ID : 20211800905082
Informations de copyright
© 2024. The Author(s), under exclusive licence to Society for Biological Inorganic Chemistry (SBIC).
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