Cost and utilization analysis of concurrent versus staged testicular prosthesis implantation for radical orchiectomy.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2024
Historique:
received: 05 11 2023
accepted: 18 12 2023
medline: 8 1 2024
pubmed: 8 1 2024
entrez: 8 1 2024
Statut: epublish

Résumé

American Urological Association guidelines recommend testicular prosthesis discussion prior to orchiectomy. Utilization may be low. We compared outcomes and care utilization between concurrent implant (CI) and staged implant (SI) insertion after radical orchiectomy. The MarketScan Commercial claims database (2008-2017) was queried for men ages >18 years who underwent radical orchiectomy for testicular mass, stratified as orchiectomy with no implant, CI, or SI. 90-day outcomes included rate of reoperation, readmission, emergency department (ED) presentation, and outpatient visits. Regression models provided rate ratio comparison. 8803 patients (8564 no implant, 190 CI, 49 SI; 2.7% implant rate) were identified with no difference in age, Charlson Comorbidity Index, insurance plan, additional cancer treatment, or metastasis. Median perioperative cost at orchiectomy (+/- implant) for no implant, CI, and SI were $5682 (3648-8554), $7823 (5403-10973), and $5380 (4130-10521), respectively (p<0.001). Median perioperative cost for SI at implantation was $8180 (4920-14591) for a total cost (orchiectomy + implant) of $13650 (5380 + 8180). CI patients were more likely to have follow-up (p = 0.006) with more visits (p = 0.030) compared to the SI group post-implantation but had similar follow-up (p = 0.065) and less visits (p = 0.025) compared to the SI patients' post-orchiectomy period. Overall explant rates were 4.7% for CI and 14.3% for SI (p = 0.04) with a median time to explant of 166 (IQR: 135-210) and 40 days (IQR: 9.5-141.5; p = 0.06). Median cost of removal was $2060 (IQR: 967-2880). CI placement has less total perioperative cost, lower explant rate, and similar postoperative utilization to SI.

Identifiants

pubmed: 38190399
doi: 10.1371/journal.pone.0296735
pii: PONE-D-23-36556
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0296735

Informations de copyright

Copyright: © 2024 Nguyen et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Déclaration de conflit d'intérêts

I have read the journal’s policy and authors of this manuscript have the following competing interests: Dr. Patel has the following to disclose: • Apta Pharma – Equity interest • Endo Pharmaceuticals – Advisor Dr. Hsieh has the following to disclose: • Boston Scientific – Advisor, consultant • Endo Pharmaceuticals – Advisor, consultant.

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Auteurs

Vi Nguyen (V)

Department of Urology, University of California, San Diego, San Diego, California, United States of America.

Arman Walia (A)

Department of Urology, University of California, San Diego, San Diego, California, United States of America.

Joshua J Horns (JJ)

Department of Urology, University of Utah, Salt Lake City, Utah, United States of America.

Niraj Paudel (N)

Department of Urology, University of Utah, Salt Lake City, Utah, United States of America.

Aditya Bagrodia (A)

Department of Urology, University of California, San Diego, San Diego, California, United States of America.

Darshan P Patel (DP)

Department of Urology, University of California, San Diego, San Diego, California, United States of America.

Tung-Chin Hsieh (TC)

Department of Urology, University of California, San Diego, San Diego, California, United States of America.

James M Hotaling (JM)

Department of Urology, University of Utah, Salt Lake City, Utah, United States of America.

Classifications MeSH