Female Genital Schistosomiasis Lesion Resolution Post-Treatment with Praziquantel in Zambian Adults.

Journal

The American journal of tropical medicine and hygiene
ISSN: 1476-1645
Titre abrégé: Am J Trop Med Hyg
Pays: United States
ID NLM: 0370507

Informations de publication

Date de publication:
09 Jan 2024
Historique:
received: 17 08 2023
accepted: 03 10 2023
medline: 8 1 2024
pubmed: 8 1 2024
entrez: 8 1 2024
Statut: aheadofprint

Résumé

We evaluated changes in female genital schistosomiasis (FGS) 6 to 12 months after praziquantel treatment among 43 adult Zambian women. Most women (60%) experienced decreased FGS severity and 23% experienced complete lesion resolution. This is the first study to demonstrate a meaningful effect of praziquantel treatment of FGS in adult women.

Identifiants

DOI: 10.4269/ajtmh.23-0552 PMID: 38190749
pubmed: 38190749
doi: 10.4269/ajtmh.23-0552
pii: tpmd230552
doi:
pii:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Chishiba Kabengele (C)

Center for Family Health Research Zambia, Lusaka, Zambia.

Sepo Mwangelwa (S)

Center for Family Health Research Zambia, Ndola, Zambia.

William Kilembe (W)

Center for Family Health Research Zambia, Lusaka, Zambia.

Bellington Vwalika (B)

Center for Family Health Research Zambia, Lusaka, Zambia.

Mubiana Inambao (M)

Center for Family Health Research Zambia, Ndola, Zambia.

Vernon Moonga (V)

Center for Family Health Research Zambia, Lusaka, Zambia.

Constance Himukumbwa (C)

Center for Family Health Research Zambia, Ndola, Zambia.

W Evan Secor (WE)

Centers for Disease Control and Prevention, Atlanta, Georgia.

Rachel Parker (R)

Rwanda Zambia HIV Research Group, Department of Pathology & Laboratory Medicine, School of Medicine and Hubert Department of Global Health, Rollins School of Public Health, Laney Graduate School, Emory University, Atlanta, Georgia.

Amanda Tichacek (A)

Rwanda Zambia HIV Research Group, Department of Pathology & Laboratory Medicine, School of Medicine and Hubert Department of Global Health, Rollins School of Public Health, Laney Graduate School, Emory University, Atlanta, Georgia.

Amaya L Bustinduy (AL)

Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, United Kingdom.

Susan Allen (S)

Rwanda Zambia HIV Research Group, Department of Pathology & Laboratory Medicine, School of Medicine and Hubert Department of Global Health, Rollins School of Public Health, Laney Graduate School, Emory University, Atlanta, Georgia.

Kristin M Wall (KM)

Rwanda Zambia HIV Research Group, Department of Pathology & Laboratory Medicine, School of Medicine and Hubert Department of Global Health, Rollins School of Public Health, Laney Graduate School, Emory University, Atlanta, Georgia.

Classifications MeSH