The TsiogkaSpaeth grid for detection of neurological visual field defects: a validation study.

Hemianopia Neurological disease The TsiogkaSpaeth grid test Visual field

Journal

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
ISSN: 1590-3478
Titre abrégé: Neurol Sci
Pays: Italy
ID NLM: 100959175

Informations de publication

Date de publication:
08 Jan 2024
Historique:
received: 29 11 2023
accepted: 02 01 2024
medline: 9 1 2024
pubmed: 9 1 2024
entrez: 8 1 2024
Statut: aheadofprint

Résumé

The TsiogkaSpaeth (TS) grid is a new, low-cost, and easy to access portable test for visual field (VF) screening which could be used by clinicians in everyday clinical practice. Our study aimed to determine the validity of an innovative screening grid test for identifying neurological disease-associated VF defects. We enrolled two groups of participants: We assessed the one eye of ten consecutive adult patients with different types of neurological disease associated VF defects and ten eyes of controls in each group. The TS grid test was performed in each group. Sensitivity, specificity, and positive and negative predictive values of the TS grid scotoma area were assessed using the 24-2 VF Humphrey field analyzer (HFA) as the reference standard. Sensitivity and specificity of the TS grid test were 100% and 90.91%, respectively. The area under curve was 0.9545 with 95% CI 0.87-1.00. There was a significant correlation between the number of missed locations on the TS grid test and the visual field index of the HFA 24-2 (r = 0.9436, P < .0001). The sensitivity and specificity of the TS grid test were high in detecting VF defects in neurological disease. The TS grid test appears to be a reliable, low-cost, and easily accessed alternative to traditional VF tests in diagnosing typical neurological patterns of visual field defects. It would be useful in screening subjects for neurologically derived ocular morbidity in everyday clinical practice and in remote areas deprived of specialized health care services.

Sections du résumé

BACKGROUND BACKGROUND
The TsiogkaSpaeth (TS) grid is a new, low-cost, and easy to access portable test for visual field (VF) screening which could be used by clinicians in everyday clinical practice. Our study aimed to determine the validity of an innovative screening grid test for identifying neurological disease-associated VF defects.
METHODS METHODS
We enrolled two groups of participants: We assessed the one eye of ten consecutive adult patients with different types of neurological disease associated VF defects and ten eyes of controls in each group. The TS grid test was performed in each group. Sensitivity, specificity, and positive and negative predictive values of the TS grid scotoma area were assessed using the 24-2 VF Humphrey field analyzer (HFA) as the reference standard.
RESULTS RESULTS
Sensitivity and specificity of the TS grid test were 100% and 90.91%, respectively. The area under curve was 0.9545 with 95% CI 0.87-1.00. There was a significant correlation between the number of missed locations on the TS grid test and the visual field index of the HFA 24-2 (r = 0.9436, P < .0001).
CONCLUSION CONCLUSIONS
The sensitivity and specificity of the TS grid test were high in detecting VF defects in neurological disease. The TS grid test appears to be a reliable, low-cost, and easily accessed alternative to traditional VF tests in diagnosing typical neurological patterns of visual field defects. It would be useful in screening subjects for neurologically derived ocular morbidity in everyday clinical practice and in remote areas deprived of specialized health care services.

Identifiants

pubmed: 38191765
doi: 10.1007/s10072-024-07305-1
pii: 10.1007/s10072-024-07305-1
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s).

Références

Rowe FJ (2016) Visual fields via the visual pathway, 2nd, edition. CRC Press, Boca Raton
Kedar S, Ghate D, Corbett JJ (2011) Visual fields in neuro-ophthalmology. Indian J Ophthalmol 59(2):103–109. https://doi.org/10.4103/0301-4738.77013
doi: 10.4103/0301-4738.77013 pubmed: 21350279 pmcid: 3116538
Hepworth LR, Rowe FJ (2018) Programme choice for perimetry in neurological conditions (PoPiN): a systematic review of perimetry options and patterns of visual field loss. BMC Ophthalmol 18(1):241. https://doi.org/10.1186/s12886-018-0912-1 . (Published)
doi: 10.1186/s12886-018-0912-1 pubmed: 30200926 pmcid: 6131852
Tsapakis S, Papaconstantinou D, Diagourtas A et al (2017) Visual field examination method using virtual reality glasses compared with the Humphrey perimeter. Clin Ophthalmol 11:1431–1443. https://doi.org/10.2147/OPTH.S131160 . (Published)
doi: 10.2147/OPTH.S131160 pubmed: 28848325 pmcid: 5557117
Wu Z, Medeiros FA (2018) Recent developments in visual field testing for glaucoma. Curr Opin Ophthalmol 29(2):141–146. https://doi.org/10.1097/ICU.0000000000000461
doi: 10.1097/ICU.0000000000000461 pubmed: 29256895
Parthasarathi P, Stokkermans TJ (2023) Tests for potential vision. In: StatPearls. StatPearls Publishing, Treasure Island
Broadway DC, Kyari F (2019) Examining visual fields. Community Eye Health 32(107):58–59
pubmed: 32123478 pmcid: 7041825
Trobe JD, Acosta PC, Krischer JP, Trick GL (1981) Confrontation visual field techniques in the detection of anterior visual pathway lesions. Ann Neurol 10(1):28–34. https://doi.org/10.1002/ana.410100105
doi: 10.1002/ana.410100105 pubmed: 7271230
Johnson LN, Baloh FG (1991) The accuracy of confrontation visual field test in comparison with automated perimetry. J Natl Med Assoc 83(10):895–898
pubmed: 1800764 pmcid: 2571584
Ruia S, Tripathy K (2023) Humphrey visual field. [Updated 2023 Aug 25]. In: StatPearls [Internet]. StatPearls Publishing, Treasure Island. Available from: https://www.ncbi.nlm.nih.gov/books/NBK585112/
Gloor BP (2009) Franz Fankhauser: the father of the automated perimeter. Surv Ophthalmol 54(3):417–425. https://doi.org/10.1016/j.survophthal.2009.02.007
doi: 10.1016/j.survophthal.2009.02.007 pubmed: 19422969
Tsapakis S, Papaconstantinou D, Diagourtas A et al (2018) Home-based visual field test for glaucoma screening comparison with Humphrey perimeter. Clin Ophthalmol 12:2597–2606. https://doi.org/10.2147/OPTH.S187832 . (Published)
doi: 10.2147/OPTH.S187832 pubmed: 30587906 pmcid: 6296209
Nakanishi M, Wang YT, Jung TP et al (2017) Detecting glaucoma with a portable brain-computer interface for objective assessment of visual function loss. JAMA Ophthalmol 135(6):550–557. https://doi.org/10.1001/jamaophthalmol.2017.0738
doi: 10.1001/jamaophthalmol.2017.0738 pubmed: 28448641 pmcid: 5772598
Wroblewski D, Francis BA, Sadun A, Vakili G, Chopra V (2014) Testing of visual field with virtual reality goggles in manual and visual grasp modes. Biomed Res Int 2014:206082. https://doi.org/10.1155/2014/206082
doi: 10.1155/2014/206082 pubmed: 25050326 pmcid: 4090491
Hollander DA, Volpe NJ, Moster ML et al (2000) Use of a portable head mounted perimetry system to assess bedside visual fields. Br J Ophthalmol 84(10):1185–1190. https://doi.org/10.1136/bjo.84.10.1185
doi: 10.1136/bjo.84.10.1185 pubmed: 11004108 pmcid: 1723249
Bengtsson B, Heijl A (2008) A visual field index for calculation of glaucoma rate of progression. Am J Ophthalmol 145(2):343–353. https://doi.org/10.1016/j.ajo.2007.09.038
doi: 10.1016/j.ajo.2007.09.038 pubmed: 18078852

Auteurs

Anastasia Tsiogka (A)

1st Department of Ophthalmology, National and Kapodistrian University of Athens, School of Medicine, General Hospital of Athens "G. Gennimatas'', Athens, Greece. Anastasia.tsioga@gmail.com.

Mark L Moster (ML)

Department of Neurology and Ophthalmology, Wills Eye Hospital and Thomas Jefferson University, Philadelphia, PA, USA.

Klio I Chatzistefanou (KI)

1st Department of Ophthalmology, National and Kapodistrian University of Athens, School of Medicine, General Hospital of Athens "G. Gennimatas'', Athens, Greece.

Efthymios Karmiris (E)

1st Department of Ophthalmology, National and Kapodistrian University of Athens, School of Medicine, General Hospital of Athens "G. Gennimatas'', Athens, Greece.
Ophthalmology Department, Hellenic Air Force General Hospital, Athens, Greece.

Evangelia Samoli (E)

Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

Ioannis Giachos (I)

1st Department of Ophthalmology, National and Kapodistrian University of Athens, School of Medicine, General Hospital of Athens "G. Gennimatas'', Athens, Greece.

Konstantinos Droutsas (K)

1st Department of Ophthalmology, National and Kapodistrian University of Athens, School of Medicine, General Hospital of Athens "G. Gennimatas'', Athens, Greece.

Dimitrios Papaconstantinou (D)

1st Department of Ophthalmology, National and Kapodistrian University of Athens, School of Medicine, General Hospital of Athens "G. Gennimatas'', Athens, Greece.

George L Spaeth (GL)

Glaucoma Service, Wills Eye Hospital, Sidney Kimmel College of Medicine, Thomas Jefferson University, Philadelphia, PA, USA.

Classifications MeSH