Range of protein induced by vitamin K absence or antagonist-II levels in neonates at birth.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
09 Jan 2024
09 Jan 2024
Historique:
received:
03
07
2023
accepted:
08
01
2024
medline:
10
1
2024
pubmed:
10
1
2024
entrez:
10
1
2024
Statut:
epublish
Résumé
Protein induced by vitamin K absence or antagonist-II (PIVKA-II) is avitamin K (VK) deficiency indicator in neonates. However, PIVKA-II detection frequency in neonatal blood at birth and the correlation between PIVKA-II and gestational age are unclear. We retrospectively analyzed infants admitted to our institution between June 1, 2018, and March 31, 2022, whose clinical and PIVKA-II data were available, and classified them into preterm and term infant groups. Overall incidence of PIVKA-II-positive cases (≥ 50 mAU/mL) was 42.8%, including 0.6% apparent VK deficiency (≥ 5000 mAU/mL), 3.1% experimental VK deficiency (1000-4999 mAU/mL), and 10.7% latent VK deficiency (200-999 mAU/mL) cases. Incidence of PIVKA-II-positive cases was significantly higher in the term group than in the preterm group (49.4% vs. 29.7%, p < 0.001). Gestational age correlated with PIVKA-II levels (r
Identifiants
pubmed: 38195988
doi: 10.1038/s41598-024-51674-8
pii: 10.1038/s41598-024-51674-8
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
921Subventions
Organisme : Japan Society for the Promotion of Science
ID : 19K17360
Organisme : Japan Society for the Promotion of Science
ID : 20K08229
Informations de copyright
© 2024. The Author(s).
Références
Motohara, K., Endo, F. & Matsuda, I. Effect of vitamin K administration on acarboxy prothrombin (PIVKA-II) levels in newborns. Lancet 2, 242–244. https://doi.org/10.1016/s0140-6736(85)90291-0 (1985).
doi: 10.1016/s0140-6736(85)90291-0
pubmed: 2862419
Humpl, T. et al. Fatal late vitamin K-deficiency bleeding after oral vitamin K prophylaxis secondary to unrecognized bile duct paucity. J. Pediatr. Gastroenterol. Nutr. 29, 594–597. https://doi.org/10.1097/00005176-199911000-00023 (1999).
doi: 10.1097/00005176-199911000-00023
pubmed: 10554130
Chuansumrit, A. et al. Prevalence of subclinical vitamin K deficiency in Thai newborns: Relationship to maternal phylloquinone intakes and delivery risk. Arch. Dis. Child Fetal Neonatal Ed. 95, F104-108. https://doi.org/10.1136/adc.2009.173245 (2010).
doi: 10.1136/adc.2009.173245
pubmed: 19822527
Belle, M., Brebant, R., Guinet, R. & Leclercq, M. Production of a new monoclonal antibody specific to human des-gamma-carboxyprothrombin in the presence of calcium ions. Application to the development of a sensitive ELISA-test. J. Immunoassay 16, 213–229. https://doi.org/10.1080/15321819508013559 (1995).
doi: 10.1080/15321819508013559
pubmed: 7629279
Greer, F. R. Vitamin K the basics–what’s new?. Early Hum. Dev. 86(Suppl 1), 43–47. https://doi.org/10.1016/j.earlhumdev.2010.01.015 (2010).
doi: 10.1016/j.earlhumdev.2010.01.015
pubmed: 20116943
Clarke, P. et al. Vitamin K prophylaxis for preterm infants: A randomized, controlled trial of 3 regimens. Pediatrics 118, e1657-1666. https://doi.org/10.1542/peds.2005-2742 (2006).
doi: 10.1542/peds.2005-2742
pubmed: 17101711
Greer, F. R. et al. A new mixed micellar preparation for oral vitamin K prophylaxis: Randomised controlled comparison with an intramuscular formulation in breast fed infants. Arch. Dis. Child 79, 300–305. https://doi.org/10.1136/adc.79.4.300 (1998).
doi: 10.1136/adc.79.4.300
pubmed: 9875038
pmcid: 1717721
Sultanik, P. et al. Diagnostic accuracy of des-gamma-carboxy prothrombin for hepatocellular carcinoma in a French cohort using the Lumipulse((R)) G600 analyzer. J. Viral Hepat. 24, 80–85. https://doi.org/10.1111/jvh.12622 (2017).
doi: 10.1111/jvh.12622
pubmed: 27699936
Caviglia, G. P. et al. Identification of the best cut-off value of PIVKA-II for the surveillance of patients at risk of hepatocellular carcinoma development. Biology (Basel) https://doi.org/10.3390/biology12010094 (2023).
doi: 10.3390/biology12010094
pubmed: 36671786
Meguro, T. & Yamada, K. A simple and rapid test for PIVKA-II in plasma. Thromb. Res. 25, 109–114. https://doi.org/10.1016/0049-3848(82)90219-5 (1982).
doi: 10.1016/0049-3848(82)90219-5
pubmed: 7064127
Shapiro, A. D. et al. Vitamin K deficiency in the newborn infant: Prevalence and perinatal risk factors. J. Pediatr. 109, 675–680. https://doi.org/10.1016/s0022-3476(86)80241-4 (1986).
doi: 10.1016/s0022-3476(86)80241-4
pubmed: 3761086
Bovill, E. G. et al. Vitamin K1 metabolism and the production of des-carboxy prothrombin and protein C in the term and premature neonate. Blood 81, 77–83 (1993).
doi: 10.1182/blood.V81.1.77.77
pubmed: 8417804
Santorino, D. et al. Prevalence and predictors of functional vitamin K insufficiency in mothers and newborns in Uganda. Nutrients 7, 8545–8552. https://doi.org/10.3390/nu7105408 (2015).
doi: 10.3390/nu7105408
pubmed: 26501317
pmcid: 4632428
Hunnali, C. R., Devi, U., Kitchanan, S. & Sethuraman, G. Three different regimens for vitamin K birth prophylaxis in infants born preterm: A randomized clinical trial. J. Pediatr. https://doi.org/10.1016/j.jpeds.2022.10.031 (2022).
doi: 10.1016/j.jpeds.2022.10.031
pubmed: 36343740
Fujioka, K. et al. Renin is activated in monochorionic diamniotic twins with birthweight discordance who do not have twin-to-twin transfusion syndrome. J. Perinatol. 32, 514–519. https://doi.org/10.1038/jp.2011.136 (2012).
doi: 10.1038/jp.2011.136
pubmed: 21941232
Itabashi, K., Miura, F., Uehara, R. & Nakamura, Y. New Japanese neonatal anthropometric charts for gestational age at birth. Pediatr. Int. 56, 702–708. https://doi.org/10.1111/ped.12331 (2014).
doi: 10.1111/ped.12331
pubmed: 24617834
Carroll, A., Desforges, M., Jones, C. J. P. & Heazell, A. E. P. Morphological and functional changes in placentas from prolonged pregnancies. Placenta 125, 29–35. https://doi.org/10.1016/j.placenta.2022.01.009 (2022).
doi: 10.1016/j.placenta.2022.01.009
pubmed: 35058067
Maiti, K. et al. Evidence that fetal death is associated with placental aging. Am. J. Obstet. Gynecol. 217(441), e441-441. https://doi.org/10.1016/j.ajog.2017.06.015 (2017).
doi: 10.1016/j.ajog.2017.06.015
Londero, A. P. et al. Placental aging and oxidation damage in a tissue micro-array model: An immunohistochemistry study. Histochem. Cell Biol. 146, 191–204. https://doi.org/10.1007/s00418-016-1435-6 (2016).
doi: 10.1007/s00418-016-1435-6
pubmed: 27106773
Mandelbrot, L. et al. Placental transfer of vitamin K1 and its implications in fetal hemostasis. Thromb. Haemost. 60, 39–43 (1988).
doi: 10.1055/s-0038-1647631
pubmed: 3187946
Shirahata, A., Itou, S., Takahashi, Y., Nishiguchi, T. & Mastuda, Y. Modified guidelline of vitamin K administration for vitamin K deficiency in infancy. J. Jpn. Pediatric Soc. 115(705), 712 (2011).
Araki, S. & Shirahata, A. Vitamin K deficiency bleeding in infancy. Nutrients https://doi.org/10.3390/nu12030780 (2020).
doi: 10.3390/nu12030780
pubmed: 33233510
pmcid: 7699484
Lembo, C., Buonocore, G. & Perrone, S. The challenge to define the optimal prophylactic regimen for vitamin K deficiency bleeding in infants. Acta Paediatr. 110, 1113–1118. https://doi.org/10.1111/apa.15566 (2021).
doi: 10.1111/apa.15566
pubmed: 32892390
Motohara, K., Kuroki, Y., Kan, H., Endo, F. & Matsuda, I. Detection of vitamin K deficiency by use of an enzyme-linked immunosorbent assay for circulating abnormal prothrombin. Pediatr. Res. 19, 354–357. https://doi.org/10.1203/00006450-198519040-00008 (1985).
doi: 10.1203/00006450-198519040-00008
pubmed: 4000762