Seropositivity, Comparison Between the Efficiency of Serological Tests and Risk Factors of Brucella Infection in Small Ruminants with History of Abortion in the Afar Region of North-Eastern Ethiopia.

abortion brucellosis seropositivity small ruminants

Journal

Veterinary medicine (Auckland, N.Z.)
ISSN: 2230-2034
Titre abrégé: Vet Med (Auckl)
Pays: New Zealand
ID NLM: 101724251

Informations de publication

Date de publication:
2023
Historique:
received: 29 10 2023
accepted: 19 12 2023
medline: 10 1 2024
pubmed: 10 1 2024
entrez: 10 1 2024
Statut: epublish

Résumé

Brucellosis is one of the most important reproductive diseases that cause abortion and breeding failure in small ruminants in Ethiopia. Therefore, our objective was to detect the seropositivity and risk factors of Sera were collected from 226 animals (195 goats and 31ewes) and assessed for seropositivity of The overall seroprevalence was 12.0% (27 out of 226), 7.5% (17 out of 226), and 26.5% (60 out of 226) by mRBPT, CFT, and cELISA, respectively. Out of 27 sera that were reactive by mRBPT, 17 (63.0%) were also reactive by (CFT). Out of the 17 sera that were reactive by CFT and mRBPT, 14 (82.4%) were reactive by cELISA. Out of the 29 sera that were non-reactive by both mRBPT and CFT, 10 (34.5%) were found reactive by cELISA. Out of the 226 sera that were tested by both mRBPT and cELISA, 20 (8.9%) were reactive by both tests, while 159 (70.4%) were non-reactive by both tests. The percentage of test agreement (79.2%) between mRBPT and cELISA was poor (k=0.353). High seropositivity for Brucella infection was significantly associated with the presence of retained placenta in the studied animals (adjusted OR=2.2, 95% CI, 1.1-4.4, P=0.030) as detected by cELISA. The current study revealed that a cELISA-based seroepidemiological survey increases the likelihood of detecting individuals with brucellosis and provides reliable evidence for mRBPT. Furthermore, there was a significant association between seropositivity for

Identifiants

pubmed: 38196943
doi: 10.2147/VMRR.S446714
pii: 446714
pmc: PMC10775148
doi:

Types de publication

Journal Article

Langues

eng

Pagination

245-252

Informations de copyright

© 2023 Tekle et al.

Déclaration de conflit d'intérêts

The authors declare that they have no competing interests

Auteurs

Muluken Tekle (M)

College of Veterinary Medicine and Agriculture, Addis Ababa University, Bishoftu, Ethiopia.

Mengistu Legesse (M)

Aklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia.

Gezahegne Mamo (G)

College of Veterinary Medicine and Agriculture, Addis Ababa University, Bishoftu, Ethiopia.

Classifications MeSH