The Effect of Vitamin D Supplementation in Pregnant Women with Overweight and Obesity: A Randomised Controlled Trial.

25OHD lipid profile obesity pregnancy vitamin D deficiency vitamin D supplement

Journal

Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595

Informations de publication

Date de publication:
31 Dec 2023
Historique:
received: 26 11 2023
revised: 27 12 2023
accepted: 29 12 2023
medline: 11 1 2024
pubmed: 11 1 2024
entrez: 11 1 2024
Statut: epublish

Résumé

The impact of vitamin D supplementation on 25-hydroxyvitamin D (25OHD) levels, metabolic status, and pregnancy outcomes in pregnant women with overweight and obesity (OW/OB) is uncertain. This study aimed to examine whether administrating 800 IU of vitamin D3 orally would improve maternal serum 25OHD levels, lipid profile, and pregnancy outcomes compared to 400 IU. This was a two-arm, parallel, non-blinded randomised controlled trial involving 274 pregnant women recruited from KK Women's and Children's Hospital, with a body mass index of ≥25 kg/m

Identifiants

pubmed: 38201976
pii: nu16010146
doi: 10.3390/nu16010146
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Temasek Foundation
ID : KRTEM2100100
Organisme : National Medical Research Council, Ministry of Health, Singapore
ID : NMRC/MOH-000596-00
Organisme : National Medical Research Council, Ministry of Health, Singapore
ID : NMRC/CSA-SI-008-2016, MOH-001266-01, MOH-001221-01 and MOH-000932-01

Auteurs

Chee Wai Ku (CW)

Department of Reproductive Medicine, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore 229899, Singapore.
Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.

Angeline Jia Wen Lee (AJW)

Lee Kong Chian School of Medicine, Nanyang Technological University, 59 Nanyang Drive, Experimental Medicine Building, Singapore 636921, Singapore.

Benjarat Oh (B)

Department of Reproductive Medicine, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore 229899, Singapore.

Celeste Hong Fei Lim (CHF)

Yong Loo Lin School of Medicine, National University of Singapore, 10 Medical Drive, Singapore 117597, Singapore.

Ting Yu Chang (TY)

Yong Loo Lin School of Medicine, National University of Singapore, 10 Medical Drive, Singapore 117597, Singapore.

Fabian Yap (F)

Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.
Lee Kong Chian School of Medicine, Nanyang Technological University, 59 Nanyang Drive, Experimental Medicine Building, Singapore 636921, Singapore.
Endocrinology Service, Department of Paediatrics, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore 229899, Singapore.

Jerry Kok Yen Chan (JKY)

Department of Reproductive Medicine, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore 229899, Singapore.
Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.

See Ling Loy (SL)

Department of Reproductive Medicine, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore 229899, Singapore.
Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.

Classifications MeSH